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CDC42SE2

GENERAL INFORMATION

Gene name

 CDC42SE2

Gene description

 CDC42 small effector 2

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 5
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 General cytoplasmic expression, most abundant in a subset of lymhocytes.

DATA RELIABILITY

Data reliability
description

 Antibody staining consistent with RNA expression data.

Reliability score

 Supported based on 1 antibody.
HPA038624
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 CDC42SE2 (HGNC Symbol)

Synonyms

 FLJ21967, SPEC2

Description

 CDC42 small effector 2 (HGNC Symbol)

Entrez gene summary

Chromosome

 5

Cytoband

 q31.1

Chromosome location (bp)

 131245493 - 131398447

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000158985 (version 83.38)

Entrez gene

 56990

UniProt

 Q9NRR3 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9NRR3

Antibodypedia

 CDC42SE2 antibodies

PROTEIN BROWSER
CDC42SE2-001
CDC42SE2-002
CDC42SE2-005
CDC42SE2-011
CDC42SE2-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
CDC42SE2-001
ENSP00000426779
ENST00000503291
D6REL0 [Direct mapping]
CDC42 small effector protein 2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0007165 [signal transduction]
Show all
 57 aa
5.9 kDa 		No 0
CDC42SE2-002
ENSP00000353706
ENST00000360515
Q9NRR3 [Direct mapping]
CDC42 small effector protein 2
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001891 [phagocytic cup]
GO:0005198 [structural molecule activity]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0005856 [cytoskeleton]
GO:0005886 [plasma membrane]
GO:0006909 [phagocytosis]
GO:0007165 [signal transduction]
GO:0008360 [regulation of cell shape]
GO:0009966 [regulation of signal transduction]
GO:0042995 [cell projection]
GO:0070062 [extracellular exosome]
Show all
 84 aa
9.2 kDa 		No 0
CDC42SE2-005
ENSP00000427421
ENST00000505065
Q9NRR3 [Direct mapping]
CDC42 small effector protein 2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001891 [phagocytic cup]
GO:0005198 [structural molecule activity]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0005856 [cytoskeleton]
GO:0005886 [plasma membrane]
GO:0006909 [phagocytosis]
GO:0007165 [signal transduction]
GO:0008360 [regulation of cell shape]
GO:0009966 [regulation of signal transduction]
GO:0042995 [cell projection]
GO:0070062 [extracellular exosome]
Show all
 84 aa
9.2 kDa 		No 0
CDC42SE2-011
ENSP00000425292
ENST00000502582
H0Y9W5 [Direct mapping]
CDC42 small effector protein 2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0007165 [signal transduction]
Show all
 54 aa
6.1 kDa 		No 0
CDC42SE2-201
ENSP00000378667
ENST00000395246
Q9NRR3 [Direct mapping]
CDC42 small effector protein 2
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001891 [phagocytic cup]
GO:0005198 [structural molecule activity]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0005856 [cytoskeleton]
GO:0005886 [plasma membrane]
GO:0006909 [phagocytosis]
GO:0007165 [signal transduction]
GO:0008360 [regulation of cell shape]
GO:0009966 [regulation of signal transduction]
GO:0042995 [cell projection]
GO:0070062 [extracellular exosome]
Show all
 84 aa
9.2 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.