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M1AP

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GENERAL INFORMATION

Gene name

 M1AP

Gene description

 Meiosis 1 associated protein

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 4
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HUMAN PROTEIN ATLAS INFORMATION

Summary

 Mainly localized to the mitochondria. In addition localized to the nucleoli.

RNA cell category

 Group enriched (NTERA-2, RT4)

Protein evidence

 Evidence at protein level

Main location

 Localized to the Mitochondria (approved)

Additional location

 In addition localized to the Nucleoli (approved)

DATA RELIABILITY

Reliability score

 Approved based on 2 antibodies.
HPA045420 , HPA059302
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ASSAYS
RNA expression
Human cells
Mouse cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Group enriched (NTERA-2, RT4)
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

HUMAN CELLS

Summary

 Mainly localized to the mitochondria. In addition localized to the nucleoli.

Main location

 Mitochondria (approved)

Additional location

 Nucleoli (approved)

 

 

 
Toggle channels
Low
High
G1
S
G2
M
N/A

Thumbnail

Antibody

Cell line

Location

Single-cell variation

Cell cycle dependent variation
HPA045420 A-431 Nucleoli
Mitochondria
HPA045420 RT4 Nucleoli
HPA045420 U-2 OS Nucleoli
Mitochondria
HPA059302 RT4 No staining    
HPA059302 SK-MEL-30 No staining    
HPA059302 U-2 OS Mitochondria

MOUSE CELLS

Main location

 Not available

Mouse gene

 ENSMUSG00000030041 (version 83)

 

 

 
Toggle channels
Low
High
G1
S
G2
M
N/A

Thumbnail

Antibody

Cell line

Location
HPA045420 NIH 3T3 No staining

GENE INFORMATION

Gene name

 M1AP (HGNC Symbol)

Synonyms

 C2orf65, D6Mm5e, SPATA37

Description

 Meiosis 1 associated protein (HGNC Symbol)

Entrez gene summary

 This gene encodes a protein that is likely to function in progression of meiosis. A similar protein in mouse plays a role in gametogenesis in both sexes. Alternate splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]

Chromosome

 2

Cytoband

 p13.1

Chromosome location (bp)

 74557883 - 74648338

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000159374 (version 83.38)

Entrez gene

 130951

UniProt

 Q8TC57 (UniProt - Evidence at protein level)

neXtProt

 NX_Q8TC57

Antibodypedia

 M1AP antibodies

PROTEIN BROWSER
M1AP-001
M1AP-002
M1AP-006
M1AP-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
M1AP-001
ENSP00000290536
ENST00000290536
Q8TC57 [Direct mapping]
Meiosis 1 arrest protein
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Show all
GO:0003674 [molecular_function]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0006396 [RNA processing]
GO:0007283 [spermatogenesis]
GO:0007292 [female gamete generation]
GO:0016021 [integral component of membrane]
GO:0030154 [cell differentiation]
GO:0031497 [chromatin assembly]
GO:0051308 [male meiosis chromosome separation]
Show all
 530 aa
59.4 kDa 		No 0
M1AP-002
ENSP00000386793
ENST00000409585
Q8TC57 [Direct mapping]
Meiosis 1 arrest protein
Show all
Predicted intracellular proteins
Show all
GO:0003674 [molecular_function]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0006396 [RNA processing]
GO:0007283 [spermatogenesis]
GO:0007292 [female gamete generation]
GO:0016021 [integral component of membrane]
GO:0030154 [cell differentiation]
GO:0031497 [chromatin assembly]
GO:0051308 [male meiosis chromosome separation]
Show all
 526 aa
58.9 kDa 		No 0
M1AP-006
ENSP00000414882
ENST00000421985
C9JPR9 [Direct mapping]
Meiosis 1 arrest protein
Show all
Predicted intracellular proteins
Show all
 142 aa
16 kDa 		No 0
M1AP-201
ENSP00000445662
ENST00000536235
Q8TC57 [Direct mapping]
Meiosis 1 arrest protein
Show all
Predicted intracellular proteins
Show all
GO:0003674 [molecular_function]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0006396 [RNA processing]
GO:0007283 [spermatogenesis]
GO:0007292 [female gamete generation]
GO:0016021 [integral component of membrane]
GO:0030154 [cell differentiation]
GO:0031497 [chromatin assembly]
GO:0051308 [male meiosis chromosome separation]
Show all
 526 aa
58.9 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.