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PGLYRP3

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GENERAL INFORMATION

Gene name

 PGLYRP3

Gene description

 Peptidoglycan recognition protein 3

Protein class

 Predicted secreted proteins

Predicted localization

 Secreted

Number of transcripts

 1
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

Summary

RNA cell category

 Group enriched (HaCaT, HDLM-2, hTCEpi)

Protein evidence

 Evidence at protein level

Main location

 Not available

DATA RELIABILITY

Reliability score

 Pending cell analysis.

ASSAYS
RNA expression

RNA EXPRESSION OVERVIEW
RNA cell line category: Group enriched (HaCaT, HDLM-2, hTCEpi)
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

GENE INFORMATION

Gene name

 PGLYRP3 (HGNC Symbol)

Synonyms

 PGLYRPIalpha, PGRP-Ialpha, PGRPIA

Description

 Peptidoglycan recognition protein 3 (HGNC Symbol)

Entrez gene summary

 This gene encodes a peptidoglycan recognition protein, which belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. These proteins are part of the innate immune system and recognize peptidoglycan, a ubiquitous component of bacterial cell walls. This antimicrobial protein binds to murein peptidoglycans of Gram-positive bacteria. [provided by RefSeq, Oct 2014]

Chromosome

 1

Cytoband

 q21.3

Chromosome location (bp)

 153297862 - 153310718

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000159527 (version 83.38)

Entrez gene

 114771

UniProt

 Q96LB9 (UniProt - Evidence at protein level)

neXtProt

 NX_Q96LB9

Antibodypedia

 PGLYRP3 antibodies

PROTEIN BROWSER
PGLYRP3-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
PGLYRP3-001
ENSP00000290722
ENST00000290722
Q96LB9 [Direct mapping]
Peptidoglycan recognition protein 3
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   MEMSAT3 predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Show all
GO:0002221 [pattern recognition receptor signaling pathway]
GO:0005576 [extracellular region]
GO:0005622 [intracellular]
GO:0008270 [zinc ion binding]
GO:0008745 [N-acetylmuramoyl-L-alanine amidase activity]
GO:0009253 [peptidoglycan catabolic process]
GO:0016019 [peptidoglycan receptor activity]
GO:0016020 [membrane]
GO:0016045 [detection of bacterium]
GO:0032689 [negative regulation of interferon-gamma production]
GO:0032827 [negative regulation of natural killer cell differentiation involved in immune response]
GO:0042834 [peptidoglycan binding]
GO:0044117 [growth of symbiont in host]
GO:0045087 [innate immune response]
GO:0050830 [defense response to Gram-positive bacterium]
Show all
 341 aa
37.6 kDa 		Yes 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.