Expression of ZBTB8A in cancer - Summary

GENERAL INFORMATION
Gene name	ZBTB8A
Gene description	Zinc finger and BTB domain containing 8A
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Ubiquitous cytoplasmic expression and a few cases of membranous staining in kidney and colon.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data.
Reliability score	Approved based on 3 antibodies. HPA031768 , HPA031769 , HPA031770
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

STAINING SUMMARY

HPA031768	HPA031769	HPA031770

GENE INFORMATION
Gene name	ZBTB8A (HGNC Symbol)
Synonyms	BOZF1, FLJ90065, ZBTB8, ZNF916A
Description	Zinc finger and BTB domain containing 8A (HGNC Symbol)
Entrez gene summary
Chromosome	1
Cytoband	p35.1
Chromosome location (bp)	32539427 - 32605939
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000160062 (version 83.38)
Entrez gene	653121
UniProt	Q96BR9 (UniProt - Evidence at protein level)
neXtProt	NX_Q96BR9
Antibodypedia	ZBTB8A antibodies

PROTEIN BROWSER

ZBTB8A-002	ZBTB8A-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ZBTB8A-002 ENSP00000362609 ENST00000373510	Q96BR9 [Direct mapping] Zinc finger and BTB domain-containing protein 8A Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0003677 [DNA binding] GO:0005515 [protein binding] GO:0005575 [cellular_component] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0008150 [biological_process] GO:0046872 [metal ion binding] Show all	441 aa 50.2 kDa	No	0
ZBTB8A-003 ENSP00000317561 ENST00000316459	D3DPQ1 [Direct mapping] HCG39683, isoform CRA_a; Zinc finger and BTB domain-containing protein 8A Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0005515 [protein binding] GO:0046872 [metal ion binding] Show all	340 aa 38.5 kDa	No	0