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Co-localization with the cis-Golgi marker GM130/GOLGA2 (RRID:AB_398141) for a refined protein localization within the Golgi apparatus in U-2 OS cells. GPSM1 localizes to the Golgi apparatus, but is only detected in the cis-Golgi compartment.
GENE INFORMATION
Gene name
GPSM1 (HGNC Symbol)
Synonyms
AGS3, DKFZP727I051
Description
G-protein signaling modulator 1 (HGNC Symbol)
Entrez gene summary
G-protein signaling modulators (GPSMs) play diverse functional roles through their interaction with G-protein subunits. This gene encodes a receptor-independent activator of G protein signaling, which is one of several factors that influence the basal activity of G-protein signaling systems. The protein contains seven tetratricopeptide repeats in its N-terminal half and four G-protein regulatory (GPR) motifs in its C-terminal half. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]