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GRASP

GENERAL INFORMATION

Gene name

 GRASP

Gene description

 GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Mixed
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 General cytoplasmic expression.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data. Pending external verification.

Reliability score

 Approved based on 1 antibody.
HPA040664
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Caudate

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 GRASP (HGNC Symbol)

Synonyms

 Tamalin

Description

 GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein (HGNC Symbol)

Entrez gene summary

 This gene encodes a protein that functions as a molecular scaffold, linking receptors, including group 1 metabotropic glutamate receptors, to neuronal proteins. The encoded protein contains conserved domains, including a leucine zipper sequence, PDZ domain and a C-terminal PDZ-binding motif. Alternately spliced transcript variants have been observed for this gene.[provided by RefSeq, Dec 2012]

Chromosome

 12

Cytoband

 q13.13

Chromosome location (bp)

 52006940 - 52015889

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000161835 (version 83.38)

Entrez gene

 160622

UniProt

 Q7Z6J2 (UniProt - Evidence at protein level)

neXtProt

 NX_Q7Z6J2

Antibodypedia

 GRASP antibodies

PROTEIN BROWSER
GRASP-001
GRASP-003
GRASP-005

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
GRASP-001
ENSP00000293662
ENST00000293662
Q7Z6J2 [Direct mapping]
General receptor for phosphoinositides 1-associated scaffold protein
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Predicted intracellular proteins
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GO:0005515 [protein binding]
GO:0005886 [plasma membrane]
GO:0007165 [signal transduction]
GO:0008104 [protein localization]
GO:0030054 [cell junction]
GO:0030165 [PDZ domain binding]
GO:0030306 [ADP-ribosylation factor binding]
GO:0042802 [identical protein binding]
GO:0045211 [postsynaptic membrane]
GO:0048471 [perinuclear region of cytoplasm]
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 395 aa
42.6 kDa 		No 0
GRASP-003
ENSP00000449492
ENST00000552049
Q7Z6J2 [Direct mapping]
General receptor for phosphoinositides 1-associated scaffold protein
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Predicted intracellular proteins
Show all
GO:0005515 [protein binding]
GO:0030054 [cell junction]
GO:0045211 [postsynaptic membrane]
GO:0048471 [perinuclear region of cytoplasm]
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 252 aa
26.9 kDa 		No 0
GRASP-005
ENSP00000448476
ENST00000546756
F8VRX5 [Direct mapping]
General receptor for phosphoinositides 1-associated scaffold protein
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Predicted intracellular proteins
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GO:0005515 [protein binding]
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 221 aa
23.1 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.