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SPC24

GENERAL INFORMATION

Gene name

 SPC24

Gene description

 SPC24, NDC80 kinetochore complex component

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 6
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Mixed
GTEx:Mixed
FANTOM5:Tissue enhanced (testis, tonsil)

Protein evidence

 Evidence at protein level

Protein expression

 Nuclear expression in a few tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data. Pending external verification.

Reliability score

 Approved based on 1 antibody.
HPA051234
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Bone marrow

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (testis, tonsil)

GENE INFORMATION

Gene name

 SPC24 (HGNC Symbol)

Synonyms

 FLJ90806, SPBC24

Description

 SPC24, NDC80 kinetochore complex component (HGNC Symbol)

Entrez gene summary

Chromosome

 19

Cytoband

 p13.2

Chromosome location (bp)

 11131520 - 11155808

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000161888 (version 83.38)

Entrez gene

 147841

UniProt

 Q8NBT2 (UniProt - Evidence at protein level)

neXtProt

 NX_Q8NBT2

Antibodypedia

 SPC24 antibodies

PROTEIN BROWSER
SPC24-001
SPC24-004
SPC24-005
SPC24-006
SPC24-007
SPC24-008

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
SPC24-001
ENSP00000465075
ENST00000592540
Q8NBT2 [Direct mapping]
Kinetochore protein Spc24
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0000278 [mitotic cell cycle]
GO:0000777 [condensed chromosome kinetochore]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005730 [nucleolus]
GO:0005829 [cytosol]
GO:0007067 [mitotic nuclear division]
GO:0007264 [small GTPase mediated signal transduction]
GO:0031262 [Ndc80 complex]
GO:0051301 [cell division]
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 197 aa
22.4 kDa 		No 0
SPC24-004
ENSP00000465167
ENST00000585486
K7EJH0 [Direct mapping]
Kinetochore protein Spc24
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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 168 aa
19 kDa 		No 0
SPC24-005
ENSP00000465335
ENST00000592967
K7EJV2 [Direct mapping]
Kinetochore protein Spc24
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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 172 aa
19.5 kDa 		No 0
SPC24-006
ENSP00000466688
ENST00000591396
K7EMX1 [Direct mapping]
Kinetochore protein Spc24
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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 171 aa
19.4 kDa 		No 0
SPC24-007
ENSP00000468366
ENST00000586708
K7ERQ7 [Direct mapping]
Kinetochore protein Spc24
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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 126 aa
13.6 kDa 		No 0
SPC24-008
ENSP00000468818
ENST00000585567
K7ESQ2 [Direct mapping]
Kinetochore protein Spc24
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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 209 aa
23.5 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.