Cell atlas - AMDHD2 - The Human Protein Atlas

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AMDHD2

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol
	Nucleoli

Human cell
	Cytosol
	Nucleoli

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GENERAL INFORMATION
Gene name	AMDHD2
Gene description	Amidohydrolase domain containing 2
Protein class	Enzymes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	7
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the nucleoli & cytosol.
RNA cell category	Mixed
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoli (approved), Cytosol (approved)
Single-cell variation	Single-cell variation in protein expression observed.

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA041184
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Mixed Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the nucleoli & cytosol.

Main location

Nucleoli (approved), Cytosol (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA041184	A-431	Nucleoli	Intensity
	HPA041184	A-431	Cytosol	Intensity
	HPA041184	U-2 OS	Nucleoli
	HPA041184	U-2 OS	Cytosol
	HPA041184	U-251 MG	Nucleoli
	HPA041184	U-251 MG	Cytosol

GENE INFORMATION
Gene name	AMDHD2 (HGNC Symbol)
Synonyms	CGI-14
Description	Amidohydrolase domain containing 2 (HGNC Symbol)
Entrez gene summary
Chromosome	16
Cytoband	p13.3
Chromosome location (bp)	2520357 - 2531422
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000162066 (version 83.38)
Entrez gene	51005
UniProt	Q9Y303 (UniProt - Evidence at protein level)
neXtProt	NX_Q9Y303
Antibodypedia	AMDHD2 antibodies

PROTEIN BROWSER

AMDHD2-001	AMDHD2-002	AMDHD2-003	AMDHD2-004	AMDHD2-011	AMDHD2-012	AMDHD2-013

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
AMDHD2-001 ENSP00000307481 ENST00000302956	Q9Y303 [Direct mapping] Putative N-acetylglucosamine-6-phosphate deacetylase Show all	Enzymes ENZYME proteins Hydrolases SCAMPI predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005975 [carbohydrate metabolic process] GO:0006044 [N-acetylglucosamine metabolic process] GO:0006046 [N-acetylglucosamine catabolic process] GO:0008448 [N-acetylglucosamine-6-phosphate deacetylase activity] GO:0016787 [hydrolase activity] GO:0016810 [hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds] GO:0019262 [N-acetylneuraminate catabolic process] GO:0046872 [metal ion binding] Show all	439 aa 46.9 kDa	No	0
AMDHD2-002 ENSP00000457136 ENST00000568263	H3BTE3 [Direct mapping] Putative N-acetylglucosamine-6-phosphate deacetylase Show all	SCAMPI predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0008152 [metabolic process] GO:0016787 [hydrolase activity] GO:0016810 [hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds] Show all	269 aa 28.5 kDa	No	0
AMDHD2-003 ENSP00000391596 ENST00000413459	Q9Y303 [Direct mapping] Putative N-acetylglucosamine-6-phosphate deacetylase Show all	Enzymes ENZYME proteins Hydrolases SCAMPI predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005975 [carbohydrate metabolic process] GO:0006046 [N-acetylglucosamine catabolic process] GO:0008448 [N-acetylglucosamine-6-phosphate deacetylase activity] GO:0016787 [hydrolase activity] GO:0016810 [hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds] GO:0019262 [N-acetylneuraminate catabolic process] GO:0046872 [metal ion binding] Show all	594 aa 63.6 kDa	No	0
AMDHD2-004 ENSP00000293971 ENST00000293971	Q9Y303 [Direct mapping] Putative N-acetylglucosamine-6-phosphate deacetylase Show all	Enzymes ENZYME proteins Hydrolases Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005975 [carbohydrate metabolic process] GO:0006044 [N-acetylglucosamine metabolic process] GO:0006046 [N-acetylglucosamine catabolic process] GO:0008448 [N-acetylglucosamine-6-phosphate deacetylase activity] GO:0016810 [hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds] GO:0019262 [N-acetylneuraminate catabolic process] GO:0046872 [metal ion binding] Show all	409 aa 43.7 kDa	No	0
AMDHD2-011 ENSP00000456898 ENST00000566706	H3BSV9 [Direct mapping] Putative N-acetylglucosamine-6-phosphate deacetylase Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0008152 [metabolic process] GO:0016810 [hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds] Show all	300 aa 31.9 kDa	No	0
AMDHD2-012 ENSP00000457398 ENST00000569879	H3BTZ6 [Direct mapping] Putative N-acetylglucosamine-6-phosphate deacetylase Show all	SCAMPI predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0008152 [metabolic process] GO:0016810 [hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds] Show all	296 aa 31.5 kDa	No	0
AMDHD2-013 ENSP00000456656 ENST00000563556	H3BSD5 [Direct mapping] Putative N-acetylglucosamine-6-phosphate deacetylase Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0008152 [metabolic process] GO:0016810 [hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds] Show all	156 aa 16.9 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.