Cell atlas - ZG16B - The Human Protein Atlas

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ZG16B

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TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Nucleoplasm
	Vesicles

Human cell
	Nucleoplasm
	Vesicles

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GENERAL INFORMATION
Gene name	ZG16B
Gene description	Zymogen granule protein 16B
Protein class	Plasma proteins Predicted intracellular proteins Predicted secreted proteins
Predicted localization	Intracellular,Secreted
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to vesicles. In addition localized to the nucleoplasm.
RNA cell category	Cell line enhanced (T-47d, MCF7, SK-BR-3)
Protein evidence	Evidence at protein level
Main location	Localized to the Vesicles (approved)
Additional location	In addition localized to the Nucleoplasm (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA053549
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (T-47d, MCF7, SK-BR-3) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to vesicles. In addition localized to the nucleoplasm.

Main location

Vesicles (approved)

Additional location

Nucleoplasm (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA053549	PC-3	Nucleoplasm
	HPA053549	PC-3	Vesicles
	HPA053549	U-2 OS	Vesicles

GENE INFORMATION
Gene name	ZG16B (HGNC Symbol)
Synonyms	HRPE773, JCLN2, PRO1567
Description	Zymogen granule protein 16B (HGNC Symbol)
Entrez gene summary
Chromosome	16
Cytoband	p13.3
Chromosome location (bp)	2830169 - 2839585
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000162078 (version 83.38)
Entrez gene	124220
UniProt	Q96DA0 (UniProt - Evidence at protein level)
neXtProt	NX_Q96DA0
Antibodypedia	ZG16B antibodies

PROTEIN BROWSER

ZG16B-001	ZG16B-002	ZG16B-005	ZG16B-006

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ZG16B-001 ENSP00000371715 ENST00000382280	Q96DA0 [Direct mapping] Zymogen granule protein 16 homolog B G8H6I3 [Target identity:100%; Query identity:100%] Endocrine and exocrine protein Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0001895 [retina homeostasis] GO:0003674 [molecular_function] GO:0005615 [extracellular space] GO:0030246 [carbohydrate binding] GO:0070062 [extracellular exosome] Show all	208 aa 22.7 kDa	Yes	0
ZG16B-002 ENSP00000460793 ENST00000570670	I3L3X0 [Direct mapping] Zymogen granule protein 16 homolog B Show all	MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		95 aa 10.2 kDa	No	0
ZG16B-005 ENSP00000458847 ENST00000571723	I3L1H9 [Direct mapping] Zymogen granule protein 16 homolog B Show all	TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all		69 aa 7.4 kDa	Yes	0
ZG16B-006 ENSP00000461740 ENST00000572863	A0A0C4DGN4 [Direct mapping] Zymogen granule protein 16 homolog B Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all		178 aa 19.6 kDa	Yes	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.