Expression of ZG16B in cancer - Summary - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

ZG16B

premium

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	ZG16B
Gene description	Zymogen granule protein 16B
Protein class	Plasma proteins Predicted intracellular proteins Predicted secreted proteins
Predicted localization	Intracellular,Secreted
Number of transcripts	4
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Tissue enhanced (prostate cancer)
HPA (cell line):	Cell line enhanced (MCF7, SK-BR-3, T-47d)
HPA (normal tissue):	Tissue enriched (salivary gland)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Selective cytoplasmic expression in salivary gland.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining consistent with RNA expression data.
Reliability score	Supported based on 2 antibodies. HPA041125 , HPA053549
	SHOW MORE

PROGNOSTIC SUMMARY
Prognostic marker in endometrial cancer (favourable).
Endometrial cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Tissue enhanced (prostate cancer)

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA041125	HPA053549

GENE INFORMATION
Gene name	ZG16B (HGNC Symbol)
Synonyms	HRPE773, JCLN2, PRO1567
Description	Zymogen granule protein 16B (HGNC Symbol)
Entrez gene summary
Chromosome	16
Cytoband	p13.3
Chromosome location (bp)	2830169 - 2839585
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000162078 (version 83.38)
Entrez gene	124220
UniProt	Q96DA0 (UniProt - Evidence at protein level)
neXtProt	NX_Q96DA0
Antibodypedia	ZG16B antibodies

PROTEIN BROWSER

ZG16B-001	ZG16B-002	ZG16B-005	ZG16B-006

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ZG16B-001 ENSP00000371715 ENST00000382280	Q96DA0 [Direct mapping] Zymogen granule protein 16 homolog B G8H6I3 [Target identity:100%; Query identity:100%] Endocrine and exocrine protein Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0001895 [retina homeostasis] GO:0003674 [molecular_function] GO:0005615 [extracellular space] GO:0030246 [carbohydrate binding] GO:0070062 [extracellular exosome] Show all	208 aa 22.7 kDa	Yes	0
ZG16B-002 ENSP00000460793 ENST00000570670	I3L3X0 [Direct mapping] Zymogen granule protein 16 homolog B Show all	MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		95 aa 10.2 kDa	No	0
ZG16B-005 ENSP00000458847 ENST00000571723	I3L1H9 [Direct mapping] Zymogen granule protein 16 homolog B Show all	TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all		69 aa 7.4 kDa	Yes	0
ZG16B-006 ENSP00000461740 ENST00000572863	A0A0C4DGN4 [Direct mapping] Zymogen granule protein 16 homolog B Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all		178 aa 19.6 kDa	Yes	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.