Tissue expression of RBP7 - Summary - The Human Protein Atlas

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RBP7

TISSUE

CELL

PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	RBP7
Gene description	Retinol binding protein 7, cellular
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enhanced (adipose tissue)
GTEx:	Group enriched (adipose tissue, breast, spleen)
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Nuclear expression in most tissues, highly abundant in adipocytes.

DATA RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data.
Reliability score	Approved based on 1 antibody. HPA034749
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (adipose tissue)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Group enriched (adipose tissue, breast, spleen)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	RBP7 (HGNC Symbol)
Synonyms	CRBPIV
Description	Retinol binding protein 7, cellular (HGNC Symbol)
Entrez gene summary	Due to its chemical instability and low solubility in aqueous solution, vitamin A requires cellular retinol-binding proteins (CRBPs), such as RBP7, for stability, internalization, intercellular transfer, homeostasis, and metabolism.[supplied by OMIM, May 2004]
Chromosome	1
Cytoband	p36.22
Chromosome location (bp)	9997206 - 10016020
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000162444 (version 83.38)
Entrez gene	116362
UniProt	Q96R05 (UniProt - Evidence at protein level)
neXtProt	NX_Q96R05
Antibodypedia	RBP7 antibodies

PROTEIN BROWSER

RBP7-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RBP7-001 ENSP00000294435 ENST00000294435	Q96R05 [Direct mapping] Retinoid-binding protein 7 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005215 [transporter activity] GO:0005501 [retinoid binding] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0006810 [transport] GO:0008289 [lipid binding] GO:0016918 [retinal binding] GO:0019841 [retinol binding] Show all	134 aa 15.5 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.