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Malignant tissues exhibited weak to moderate immunoreactivity. Occasional cases of ovarian, cervical, breast and pancreatic cancers showed strong staining. Several cases of testicular and renal cancers were negative.
GENE INFORMATION
Gene name
GBP4 (HGNC Symbol)
Synonyms
Mpa2
Description
Guanylate binding protein 4 (HGNC Symbol)
Entrez gene summary
Guanylate-binding proteins, such as GBP4, are induced by interferon and hydrolyze GTP to both GDP and GMP (Vestal, 2005 [PubMed 16108726]).[supplied by OMIM, Dec 2008]
Q96PP9 [Direct mapping] Guanylate-binding protein 4
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MEMSAT3 predicted membrane proteins Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)