Cell atlas - IER5 - The Human Protein Atlas

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IER5

TISSUE

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CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Nucleoli
	Nucleus

Human cell
	Nucleoli
	Nucleoplasm

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GENERAL INFORMATION
Gene name	IER5
Gene description	Immediate early response 5
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the nucleus & nucleoli.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleus (supported), Nucleoli (supported)

DATA RELIABILITY
Reliability score	Supported based on 1 antibody. HPA029894
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the nucleus & nucleoli.

Main location

Nucleus (supported), Nucleoli (supported)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA029894	A-431	Nucleus
	HPA029894	U-2 OS	Nucleus
	HPA029894	U-251 MG	Nucleus
	HPA029894	U-251 MG	Nucleoli

GENE INFORMATION
Gene name	IER5
Synonyms
Description	Immediate early response 5 (HGNC Symbol)
Entrez gene summary	This gene encodes a protein that is similar to other immediate early response proteins. In the mouse, a similar gene may play an important role in mediating the cellular response to mitogenic signals. Studies in rats found the expression of a similar gene to be increased after waking and sleep deprivation. [provided by RefSeq, Jul 2008]
Chromosome	1
Cytoband	q25.3
Chromosome location (bp)	181088712 - 181092899
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000162783 (version 83.38)
Entrez gene	51278
UniProt	Q5VY09 (UniProt - Evidence at transcript level)
neXtProt	NX_Q5VY09
Antibodypedia	IER5 antibodies

PROTEIN BROWSER

IER5-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
IER5-001 ENSP00000356549 ENST00000367577	Q5VY09 [Direct mapping] Immediate early response gene 5 protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		327 aa 33.7 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.