Tissue expression of DHX57 - Summary - The Human Protein Atlas

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DHX57

TISSUE

CELL

PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	DHX57
Gene description	DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
Protein class	Enzymes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Mixed
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

Protein expression

RNA-based expert annotation gave inconclusive results.

DATA RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA036160
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Mixed
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	DHX57 (HGNC Symbol)
Synonyms	DDX57
Description	DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 (HGNC Symbol)
Entrez gene summary
Chromosome	2
Cytoband	p22.1
Chromosome location (bp)	38797729 - 38875934
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000163214 (version 83.38)
Entrez gene	90957
UniProt	Q6P158 (UniProt - Evidence at protein level)
neXtProt	NX_Q6P158
Antibodypedia	DHX57 antibodies

PROTEIN BROWSER

DHX57-001	DHX57-005	DHX57-010	DHX57-011

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
DHX57-001 ENSP00000405111 ENST00000457308	Q6P158 [Direct mapping] Putative ATP-dependent RNA helicase DHX57 Show all	Enzymes ENZYME proteins Hydrolases MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0004004 [ATP-dependent RNA helicase activity] GO:0004386 [helicase activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0005737 [cytoplasm] GO:0005739 [mitochondrion] GO:0006396 [RNA processing] GO:0008026 [ATP-dependent helicase activity] GO:0044822 [poly(A) RNA binding] GO:0046872 [metal ion binding] Show all	1386 aa 155.6 kDa	No	0
DHX57-005 ENSP00000479840 ENST00000619207	A0A087WW12 [Direct mapping] Putative ATP-dependent RNA helicase DHX57 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004004 [ATP-dependent RNA helicase activity] GO:0005737 [cytoplasm] GO:0005739 [mitochondrion] GO:0006396 [RNA processing] Show all	106 aa 11.8 kDa	No	0
DHX57-010 ENSP00000397841 ENST00000452978	H7C109 [Direct mapping] Putative ATP-dependent RNA helicase DHX57 Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004004 [ATP-dependent RNA helicase activity] GO:0004386 [helicase activity] GO:0005737 [cytoplasm] GO:0005739 [mitochondrion] GO:0006396 [RNA processing] Show all	665 aa 74.9 kDa	No	0
DHX57-011 ENSP00000387404 ENST00000442331	H7BZ23 [Direct mapping] Putative ATP-dependent RNA helicase DHX57 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004004 [ATP-dependent RNA helicase activity] GO:0005737 [cytoplasm] GO:0005739 [mitochondrion] GO:0006396 [RNA processing] Show all	51 aa 6 kDa	No	0

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.