Tissue expression of PGLYRP4 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	PGLYRP4
Gene description	Peptidoglycan recognition protein 4
Protein class	Predicted secreted proteins
Predicted localization	Secreted
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Group enriched (esophagus, skin)
GTEx:	Group enriched (cervix, uterine, esophagus, skin, vagina)
FANTOM5:	Tissue enhanced (cervix, uterine, esophagus, tonsil)

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Group enriched (esophagus, skin)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Group enriched (cervix, uterine, esophagus, skin, vagina)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (cervix, uterine, esophagus, tonsil)

GENE INFORMATION
Gene name	PGLYRP4 (HGNC Symbol)
Synonyms	PGLYRPIbeta, PGRP-Ibeta, PGRPIB, SBBI67
Description	Peptidoglycan recognition protein 4 (HGNC Symbol)
Entrez gene summary	Summary: This gene encodes a peptidoglycan recognition protein, which belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. These proteins are part of the innate immune system and recognize peptidoglycan, a ubiquitous component of bacterial cell walls. This antimicrobial protein binds to murein peptidoglycans of Gram-positive bacteria. [provided by RefSeq, Oct 2014]
Chromosome	1
Cytoband	q21.3
Chromosome location (bp)	153330120 - 153348840
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000163218 (version 83.38)
Entrez gene	57115
UniProt	Q96LB8 (UniProt - Evidence at protein level)
neXtProt	NX_Q96LB8
Antibodypedia	PGLYRP4 antibodies

PROTEIN BROWSER

PGLYRP4-001	PGLYRP4-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PGLYRP4-001 ENSP00000352672 ENST00000359650	Q96LB8 [Direct mapping] Peptidoglycan recognition protein 4 Show all	MEMSAT3 predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0002221 [pattern recognition receptor signaling pathway] GO:0005576 [extracellular region] GO:0005622 [intracellular] GO:0008270 [zinc ion binding] GO:0008745 [N-acetylmuramoyl-L-alanine amidase activity] GO:0009253 [peptidoglycan catabolic process] GO:0016019 [peptidoglycan receptor activity] GO:0016020 [membrane] GO:0016045 [detection of bacterium] GO:0032689 [negative regulation of interferon-gamma production] GO:0032827 [negative regulation of natural killer cell differentiation involved in immune response] GO:0042834 [peptidoglycan binding] GO:0044117 [growth of symbiont in host] GO:0045087 [innate immune response] GO:0050830 [defense response to Gram-positive bacterium] Show all	373 aa 40.6 kDa	Yes	0
PGLYRP4-002 ENSP00000357728 ENST00000368739	Q96LB8 [Direct mapping] Peptidoglycan recognition protein 4 Show all	MEMSAT3 predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0002221 [pattern recognition receptor signaling pathway] GO:0005576 [extracellular region] GO:0005622 [intracellular] GO:0008270 [zinc ion binding] GO:0008745 [N-acetylmuramoyl-L-alanine amidase activity] GO:0009253 [peptidoglycan catabolic process] GO:0016019 [peptidoglycan receptor activity] GO:0016020 [membrane] GO:0016045 [detection of bacterium] GO:0042834 [peptidoglycan binding] GO:0045087 [innate immune response] GO:0050830 [defense response to Gram-positive bacterium] Show all	369 aa 40.3 kDa	Yes	0