Cell atlas - MRPS18C - The Human Protein Atlas

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MRPS18C

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	MRPS18C
Gene description	Mitochondrial ribosomal protein S18C
Protein class	Predicted intracellular proteins Ribosomal proteins
Predicted localization	Intracellular
Number of transcripts	5
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	MRPS18C (HGNC Symbol)
Synonyms	CGI-134, FLJ11146, FLJ22967, MRPS18-1
Description	Mitochondrial ribosomal protein S18C (HGNC Symbol)
Entrez gene summary	Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S18P family. The encoded protein is one of three that has significant sequence similarity to bacterial S18 proteins. The primary sequences of the three human mitochondrial S18 proteins are no more closely related to each other than they are to the prokaryotic S18 proteins. Pseudogenes corresponding to this gene are found on chromosomes 8p, 12p, 15q, and 22q. [provided by RefSeq, Jul 2008]
Chromosome	4
Cytoband	q21.23
Chromosome location (bp)	83455932 - 83469735
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000163319 (version 83.38)
Entrez gene	51023
UniProt	Q9Y3D5 (UniProt - Evidence at protein level)
neXtProt	NX_Q9Y3D5
Antibodypedia	MRPS18C antibodies

PROTEIN BROWSER

MRPS18C-001	MRPS18C-003	MRPS18C-005	MRPS18C-006	MRPS18C-010

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
MRPS18C-001 ENSP00000295491 ENST00000295491	Q9Y3D5 [Direct mapping] 28S ribosomal protein S18c, mitochondrial A0A024RDH9 [Target identity:100%; Query identity:100%] Mitochondrial ribosomal protein S18C, isoform CRA_b Show all	Ribosomal proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003735 [structural constituent of ribosome] GO:0005622 [intracellular] GO:0005739 [mitochondrion] GO:0005743 [mitochondrial inner membrane] GO:0005763 [mitochondrial small ribosomal subunit] GO:0005840 [ribosome] GO:0006412 [translation] GO:0006996 [organelle organization] GO:0032543 [mitochondrial translation] GO:0070124 [mitochondrial translational initiation] GO:0070125 [mitochondrial translational elongation] GO:0070126 [mitochondrial translational termination] Show all	142 aa 15.8 kDa	No	0
MRPS18C-003 ENSP00000427169 ENST00000507019	D6RCM2 [Direct mapping] 28S ribosomal protein S18c, mitochondrial; Mitochondrial ribosomal protein S18C, isoform CRA_c Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003735 [structural constituent of ribosome] GO:0005622 [intracellular] GO:0005840 [ribosome] GO:0006412 [translation] Show all	114 aa 12.6 kDa	No	0
MRPS18C-005 ENSP00000425268 ENST00000505719	H0Y9W2 [Direct mapping] 28S ribosomal protein S18c, mitochondrial Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003735 [structural constituent of ribosome] GO:0005840 [ribosome] GO:0006412 [translation] Show all	92 aa 10.3 kDa	No	0
MRPS18C-006 ENSP00000426930 ENST00000507349	D6RE70 [Direct mapping] 28S ribosomal protein S18c, mitochondrial Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003735 [structural constituent of ribosome] GO:0006412 [translation] Show all	68 aa 7.5 kDa	No	0
MRPS18C-010 ENSP00000427014 ENST00000509970	H0YAG5 [Direct mapping] 28S ribosomal protein S18c, mitochondrial Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003735 [structural constituent of ribosome] GO:0005622 [intracellular] GO:0005840 [ribosome] GO:0006412 [translation] Show all	113 aa 12.4 kDa	No	0

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.