Tissue expression of FEV - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	FEV
Gene description	FEV (ETS oncogene family)
Protein class	Cancer-related genes Disease related genes Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enhanced (adrenal gland, duodenum, stomach)
GTEx:	Tissue enhanced (pituitary gland, prostate)
FANTOM5:	Tissue enhanced (colon, small intestine)

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (adrenal gland, duodenum, stomach)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (pituitary gland, prostate)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (colon, small intestine)

GENE INFORMATION
Gene name	FEV (HGNC Symbol)
Synonyms	Pet-1
Description	FEV (ETS oncogene family) (HGNC Symbol)
Entrez gene summary	This gene belongs to the ETS transcription factor family. ETS family members have a highly conserved 85-amino acid ETS domain that binds purine-rich DNA sequences. The alanine-rich C-terminus of this gene indicates that it may act as a transcription repressor. This gene is exclusively expressed in neurons of the central serotonin (5-HT) system, a system implicated in the pathogeny of such psychiatric diseases as depression, anxiety, and eating disorders. In some types of Ewing tumors, this gene is fused to the Ewing sarcoma (EWS) gene following chromosome translocations. [provided by RefSeq, Jul 2008]
Chromosome	2
Cytoband	q35
Chromosome location (bp)	218981087 - 218985657
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000163497 (version 83.38)
Entrez gene	54738
UniProt	Q99581 (UniProt - Evidence at protein level)
neXtProt	NX_Q99581
Antibodypedia	FEV antibodies

PROTEIN BROWSER

FEV-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FEV-001 ENSP00000295727 ENST00000295727	Q99581 [Direct mapping] Protein FEV Show all	Predicted intracellular proteins Transcription factors Helix-turn-helix domains Cancer-related genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Disease related genes Show all	GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0003714 [transcription corepressor activity] GO:0005634 [nucleus] GO:0006355 [regulation of transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0006366 [transcription from RNA polymerase II promoter] GO:0010628 [positive regulation of gene expression] GO:0030154 [cell differentiation] GO:0042551 [neuron maturation] GO:0043565 [sequence-specific DNA binding] GO:0048665 [neuron fate specification] GO:1903507 [negative regulation of nucleic acid-templated transcription] Show all	238 aa 25 kDa	No	0