Expression of KIAA1143 in cancer - Summary - The Human Protein Atlas

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KIAA1143

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	KIAA1143
Gene description	KIAA1143
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression in most tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 1 antibody. HPA045018
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (favourable) and colorectal cancer (favourable).
Renal cancer p<0.001 Colorectal cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA045018

GENE INFORMATION
Gene name	KIAA1143
Synonyms
Description	KIAA1143 (HGNC Symbol)
Entrez gene summary
Chromosome	3
Cytoband	p21.31
Chromosome location (bp)	44737661 - 44761662
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000163807 (version 83.38)
Entrez gene	57456
UniProt	Q96AT1 (UniProt - Evidence at protein level)
neXtProt	NX_Q96AT1
Antibodypedia	KIAA1143 antibodies

PROTEIN BROWSER

KIAA1143-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
KIAA1143-001 ENSP00000296121 ENST00000296121	Q96AT1 [Direct mapping] Uncharacterized protein KIAA1143 A0A024R2T2 [Target identity:100%; Query identity:100%] KIAA1143, isoform CRA_a Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	154 aa 17.5 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.