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CLEC3B

GENERAL INFORMATION

Gene name

 CLEC3B

Gene description

 C-type lectin domain family 3, member B

Protein class

 Cancer-related genes
Plasma proteins
Predicted intracellular proteins
Predicted secreted proteins

Predicted localization

 Intracellular,Secreted

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enhanced (spleen)
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Plasma positivity in most tissues.

DATA RELIABILITY

Data reliability
description

 Secreted protein, tissue location of RNA and protein might differ and correlation is complex.

Reliability score

 Approved based on 2 antibodies.
HPA034794 , CAB002582
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (spleen)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 CLEC3B (HGNC Symbol)

Synonyms

 TN, TNA

Description

 C-type lectin domain family 3, member B (HGNC Symbol)

Entrez gene summary

Chromosome

 3

Cytoband

 p21.31

Chromosome location (bp)

 45001548 - 45036071

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000163815 (version 83.38)

Entrez gene

 7123

UniProt

 P05452 (UniProt - Evidence at protein level)

neXtProt

 NX_P05452

Antibodypedia

 CLEC3B antibodies

PROTEIN BROWSER
CLEC3B-001
CLEC3B-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
CLEC3B-001
ENSP00000296130
ENST00000296130
P05452 [Direct mapping]
Tetranectin
A0A024R2Q7 [Target identity:100%; Query identity:100%]
C-type lectin domain family 3, member B, isoform CRA_a
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   MEMSAT3 predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0001501 [skeletal system development]
GO:0001503 [ossification]
GO:0001652 [granular component]
GO:0005509 [calcium ion binding]
GO:0005576 [extracellular region]
GO:0005615 [extracellular space]
GO:0005737 [cytoplasm]
GO:0008201 [heparin binding]
GO:0010756 [positive regulation of plasminogen activation]
GO:0030246 [carbohydrate binding]
GO:0030282 [bone mineralization]
GO:0031012 [extracellular matrix]
GO:0036143 [kringle domain binding]
GO:0070062 [extracellular exosome]
GO:0071310 [cellular response to organic substance]
GO:0071560 [cellular response to transforming growth factor beta stimulus]
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 202 aa
22.5 kDa 		Yes 0
CLEC3B-002
ENSP00000396013
ENST00000428034
E9PHK0 [Direct mapping]
Tetranectin
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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 160 aa
17.8 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.