Cell atlas - BDH2 - The Human Protein Atlas

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BDH2

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TISSUE

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CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol

Human cell
	Cytosol

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GENERAL INFORMATION
Gene name	BDH2
Gene description	3-hydroxybutyrate dehydrogenase, type 2
Protein class	Enzymes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the cytosol.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Cytosol (supported)

DATA RELIABILITY
Reliability score	Supported based on 1 antibody. HPA036029
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the cytosol.

Main location

Cytosol (supported)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA036029	A-431	Cytosol
	HPA036029	U-2 OS	Cytosol
	HPA036029	U-251 MG	Cytosol

GENE INFORMATION
Gene name	BDH2 (HGNC Symbol)
Synonyms	DHRS6, FLJ13261, PRO20933, SDR15C1, UCPA-OR, UNQ6308
Description	3-hydroxybutyrate dehydrogenase, type 2 (HGNC Symbol)
Entrez gene summary
Chromosome	4
Cytoband	q24
Chromosome location (bp)	103079435 - 103099883
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000164039 (version 83.38)
Entrez gene	56898
UniProt	Q9BUT1 (UniProt - Evidence at protein level)
neXtProt	NX_Q9BUT1
Antibodypedia	BDH2 antibodies

PROTEIN BROWSER

BDH2-001	BDH2-006	BDH2-007

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
BDH2-001 ENSP00000296424 ENST00000296424	Q9BUT1 [Direct mapping] 3-hydroxybutyrate dehydrogenase type 2 A0A024RDG9 [Target identity:100%; Query identity:100%] 3-hydroxybutyrate dehydrogenase, type 2, isoform CRA_b Show all	Enzymes ENZYME proteins Oxidoreductases Phobius predicted secreted proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003858 [3-hydroxybutyrate dehydrogenase activity] GO:0005737 [cytoplasm] GO:0005829 [cytosol] GO:0006635 [fatty acid beta-oxidation] GO:0016491 [oxidoreductase activity] GO:0016628 [oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor] GO:0019290 [siderophore biosynthetic process] GO:0030855 [epithelial cell differentiation] GO:0042168 [heme metabolic process] GO:0044255 [cellular lipid metabolic process] GO:0044281 [small molecule metabolic process] GO:0046950 [cellular ketone body metabolic process] GO:0046951 [ketone body biosynthetic process] GO:0051287 [NAD binding] GO:0055072 [iron ion homeostasis] GO:0070062 [extracellular exosome] Show all	245 aa 26.7 kDa	No	0
BDH2-006 ENSP00000422891 ENST00000509245	D6R9U8 [Direct mapping] 3-hydroxybutyrate dehydrogenase type 2 Show all	SPOCTOPUS predicted membrane proteins Phobius predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005737 [cytoplasm] GO:0008152 [metabolic process] GO:0008667 [2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase activity] GO:0016491 [oxidoreductase activity] GO:0019290 [siderophore biosynthetic process] GO:0055114 [oxidation-reduction process] Show all	116 aa 12.9 kDa	No	0
BDH2-007 ENSP00000427442 ENST00000504285	D6RIR6 [Direct mapping] 3-hydroxybutyrate dehydrogenase type 2 Show all	SPOCTOPUS predicted membrane proteins Phobius predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005737 [cytoplasm] GO:0008152 [metabolic process] GO:0016491 [oxidoreductase activity] GO:0055114 [oxidation-reduction process] Show all	130 aa 14.4 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.