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SCRG1

GENERAL INFORMATION

Gene name

 SCRG1

Gene description

 Stimulator of chondrogenesis 1

Protein class

 Predicted secreted proteins

Predicted localization

 Secreted

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enhanced (cerebral cortex, testis)
GTEx:Tissue enhanced (caudate)
FANTOM5:Tissue enhanced (brain, caudate, hippocampus)

Protein evidence

 Evidence at protein level

Protein expression

 General cytoplasmic expression.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data.

Reliability score

 Approved based on 1 antibody.
HPA012882
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (cerebral cortex, testis)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (caudate)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (brain, caudate, hippocampus)

GENE INFORMATION

Gene name

 SCRG1 (HGNC Symbol)

Synonyms

 SCRG-1

Description

 Stimulator of chondrogenesis 1 (HGNC Symbol)

Entrez gene summary

 Scrapie-responsive gene 1 is associated with neurodegenerative changes observed in transmissible spongiform encephalopathies. It may play a role in host response to prion-associated infections. The scrapie responsive protein 1 may be partly included in the membrane or secreted by the cells due to its hydrophobic N-terminus. [provided by RefSeq, Jul 2008]

Chromosome

 4

Cytoband

 q34.1

Chromosome location (bp)

 173384701 - 173406380

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000164106 (version 83.38)

Entrez gene

 11341

UniProt

 O75711 (UniProt - Evidence at protein level)

neXtProt

 NX_O75711

Antibodypedia

 SCRG1 antibodies

PROTEIN BROWSER
SCRG1-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
SCRG1-001
ENSP00000296506
ENST00000296506
O75711 [Direct mapping]
Scrapie-responsive protein 1
Q6FGG5 [Target identity:100%; Query identity:100%]
SCRG1 protein; Scrapie responsive protein 1, isoform CRA_a; cDNA, FLJ92430, Homo sapiens scrapie responsive protein 1 (SCRG1), mRNA
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   MEMSAT3 predicted membrane proteins
   TMHMM predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
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GO:0005515 [protein binding]
GO:0005615 [extracellular space]
GO:0007399 [nervous system development]
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 98 aa
11.1 kDa 		Yes 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.