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Most of the malignant cells displayed weak to moderate nuclear positivity with additional cytoplasmic and/or membranous staining in several cases. Several lymphomas, renal, skin and liver cancers were negative.
GENE INFORMATION
Gene name
ICE1 (HGNC Symbol)
Synonyms
KIAA0947
Description
Interactor of little elongation complex ELL subunit 1 (HGNC Symbol)
Q9Y2F5 [Direct mapping] Little elongation complex subunit 1
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Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
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GO:0005515 [protein binding] GO:0008023 [transcription elongation factor complex] GO:0015030 [Cajal body] GO:0031334 [positive regulation of protein complex assembly] GO:0035327 [transcriptionally active chromatin] GO:0035363 [histone locus body] GO:0042795 [snRNA transcription from RNA polymerase II promoter] GO:0042796 [snRNA transcription from RNA polymerase III promoter] GO:0042803 [protein homodimerization activity] GO:0045945 [positive regulation of transcription from RNA polymerase III promoter] GO:0090316 [positive regulation of intracellular protein transport]