Cell atlas - SPZ1 - The Human Protein Atlas

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SPZ1

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	SPZ1
Gene description	Spermatogenic leucine zipper 1
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Not detected
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Not detected Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	SPZ1 (HGNC Symbol)
Synonyms	FLJ25709, NYD-TSP1, PPP1R148
Description	Spermatogenic leucine zipper 1 (HGNC Symbol)
Entrez gene summary	This gene encodes a bHLH-zip transcription factor which functions in the mitogen-activate protein kinase (MAPK) signaling pathway. Because of its role in the upregulation of cell proliferation and tumorigenesis, this gene may serve as a target for Ras-induced tumor treatments. [provided by RefSeq, Oct 2011]
Chromosome	5
Cytoband	q14.1
Chromosome location (bp)	80319625 - 80321842
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000164299 (version 83.38)
Entrez gene	84654
UniProt	Q9BXG8 (UniProt - Evidence at protein level)
neXtProt	NX_Q9BXG8
Antibodypedia	SPZ1 antibodies

PROTEIN BROWSER

SPZ1-001	SPZ1-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SPZ1-001 ENSP00000369611 ENST00000296739	Q9BXG8 [Direct mapping] Spermatogenic leucine zipper protein 1 Show all	MEMSAT3 predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0003677 [DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] Show all	430 aa 49.4 kDa	No	0
SPZ1-003 ENSP00000426530 ENST00000511881	D6RFL8 [Direct mapping] Spermatogenic leucine zipper protein 1 Show all	MEMSAT3 predicted membrane proteins Predicted intracellular proteins Show all	GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005634 [nucleus] GO:0006355 [regulation of transcription, DNA-templated] Show all	234 aa 26.6 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.