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PI16

GENERAL INFORMATION

Gene name

 PI16

Gene description

 Peptidase inhibitor 16

Protein class

 Plasma proteins
Predicted membrane proteins

Predicted localization

 Membrane

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enhanced (cervix, uterine)
GTEx:Tissue enhanced (vagina)
FANTOM5:Tissue enhanced (retina)

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic and membranous expression in most tissues.

DATA RELIABILITY

Data reliability
description

 Pending external verification.

Reliability score

 Uncertain based on 1 antibody.
HPA043763
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Stomach

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (cervix, uterine)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (vagina)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (retina)

GENE INFORMATION

Gene name

 PI16 (HGNC Symbol)

Synonyms

 CD364, dJ90K10.5, MGC45378, MSMBBP

Description

 Peptidase inhibitor 16 (HGNC Symbol)

Entrez gene summary

Chromosome

 6

Cytoband

 p21.2

Chromosome location (bp)

 36948263 - 36964837

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000164530 (version 83.38)

Entrez gene

 221476

UniProt

 Q6UXB8 (UniProt - Evidence at protein level)

neXtProt

 NX_Q6UXB8

Antibodypedia

 PI16 antibodies

PROTEIN BROWSER
PI16-001
PI16-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
PI16-001
ENSP00000362778
ENST00000373674
Q6UXB8 [Direct mapping]
Peptidase inhibitor 16
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Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005576 [extracellular region]
GO:0005615 [extracellular space]
GO:0010466 [negative regulation of peptidase activity]
GO:0016021 [integral component of membrane]
GO:0030414 [peptidase inhibitor activity]
GO:0061052 [negative regulation of cell growth involved in cardiac muscle cell development]
GO:0070062 [extracellular exosome]
Show all
 463 aa
49.5 kDa 		Yes 1
PI16-201
ENSP00000478888
ENST00000611814
Q6UXB8 [Direct mapping]
Peptidase inhibitor 16
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005576 [extracellular region]
GO:0010466 [negative regulation of peptidase activity]
GO:0016021 [integral component of membrane]
GO:0030414 [peptidase inhibitor activity]
GO:0070062 [extracellular exosome]
Show all
 463 aa
49.5 kDa 		Yes 1

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.