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GALNT10

GENERAL INFORMATION

Gene name

 GALNT10

Gene description

 Polypeptide N-acetylgalactosaminyltransferase 10

Protein class

 Enzymes
Predicted secreted proteins

Predicted localization

 Secreted

Number of transcripts

 3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression in most tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data.

Reliability score

 Approved based on 1 antibody.
HPA007525
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 GALNT10 (HGNC Symbol)

Synonyms

 GalNAc-T10

Description

 Polypeptide N-acetylgalactosaminyltransferase 10 (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of the GalNAc polypeptide N-acetylgalactosaminyltransferases. These enzymes catalyze the first step in the synthesis of mucin-type oligosaccharides. These proteins transfer GalNAc from UDP-GalNAc to either serine or threonine residues of polypeptide acceptors. The protein encoded by this locus may have increased catalytic activity toward glycosylated peptides compared to activity toward non-glycosylated peptides.[provided by RefSeq, Apr 2010]

Chromosome

 5

Cytoband

 q33.2

Chromosome location (bp)

 154190730 - 154420984

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000164574 (version 83.38)

Entrez gene

 55568

UniProt

 Q86SR1 (UniProt - Evidence at protein level)

neXtProt

 NX_Q86SR1

Antibodypedia

 GALNT10 antibodies

PROTEIN BROWSER
GALNT10-001
GALNT10-003
GALNT10-005

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
GALNT10-001
ENSP00000297107
ENST00000297107
Q86SR1 [Direct mapping]
Polypeptide N-acetylgalactosaminyltransferase 10
Show all
Enzymes
   ENZYME proteins
   Transferases
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000139 [Golgi membrane]
GO:0004653 [polypeptide N-acetylgalactosaminyltransferase activity]
GO:0006493 [protein O-linked glycosylation]
GO:0016021 [integral component of membrane]
GO:0016266 [O-glycan processing]
GO:0030246 [carbohydrate binding]
GO:0043687 [post-translational protein modification]
GO:0044267 [cellular protein metabolic process]
GO:0046872 [metal ion binding]
Show all
 603 aa
69 kDa 		Yes 0
GALNT10-003
ENSP00000366889
ENST00000377661
Q86SR1 [Direct mapping]
Polypeptide N-acetylgalactosaminyltransferase 10
Show all
Enzymes
   ENZYME proteins
   Transferases
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000139 [Golgi membrane]
GO:0004653 [polypeptide N-acetylgalactosaminyltransferase activity]
GO:0006493 [protein O-linked glycosylation]
GO:0016021 [integral component of membrane]
GO:0016266 [O-glycan processing]
GO:0030246 [carbohydrate binding]
GO:0043687 [post-translational protein modification]
GO:0044267 [cellular protein metabolic process]
GO:0046872 [metal ion binding]
Show all
 541 aa
61.9 kDa 		Yes 0
GALNT10-005
ENSP00000415210
ENST00000425427
Q86SR1 [Direct mapping]
Polypeptide N-acetylgalactosaminyltransferase 10
Show all
Enzymes
   ENZYME proteins
   Transferases
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000139 [Golgi membrane]
GO:0004653 [polypeptide N-acetylgalactosaminyltransferase activity]
GO:0006493 [protein O-linked glycosylation]
GO:0016021 [integral component of membrane]
GO:0016266 [O-glycan processing]
GO:0030246 [carbohydrate binding]
GO:0043687 [post-translational protein modification]
GO:0044267 [cellular protein metabolic process]
GO:0046872 [metal ion binding]
Show all
 366 aa
41.5 kDa 		Yes 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.