Tissue expression of NEUROD6 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	NEUROD6
Gene description	Neuronal differentiation 6
Protein class	Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enriched (cerebral cortex)
GTEx:	Group enriched (cerebral cortex, hippocampus)
FANTOM5:	Group enriched (brain, hippocampus)

Protein evidence

Evidence at transcript level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (cerebral cortex)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Group enriched (cerebral cortex, hippocampus)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Group enriched (brain, hippocampus)

GENE INFORMATION
Gene name	NEUROD6 (HGNC Symbol)
Synonyms	Atoh2, bHLHa2, Math-2, Nex1, NEX1M
Description	Neuronal differentiation 6 (HGNC Symbol)
Entrez gene summary	This gene is a member of the NEUROD family of basic helix-loop-helix transcription factors. The encoded protein may be involved in the development and differentiation of the nervous system. [provided by RefSeq, Nov 2012]
Chromosome	7
Cytoband	p14.3
Chromosome location (bp)	31337461 - 31340894
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000164600 (version 83.38)
Entrez gene	63974
UniProt	Q96NK8 (UniProt - Evidence at transcript level)
neXtProt	NX_Q96NK8
Antibodypedia	NEUROD6 antibodies

PROTEIN BROWSER

NEUROD6-001	NEUROD6-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
NEUROD6-001 ENSP00000297142 ENST00000297142	Q96NK8 [Direct mapping] Neurogenic differentiation factor 6 A0A090N7T3 [Target identity:100%; Query identity:100%] Neurogenic differentiation factor Show all	Predicted intracellular proteins Transcription factors Basic domains Show all	GO:0000978 [RNA polymerase II core promoter proximal region sequence-specific DNA binding] GO:0001077 [transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding] GO:0005634 [nucleus] GO:0006366 [transcription from RNA polymerase II promoter] GO:0021542 [dentate gyrus development] GO:0030154 [cell differentiation] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0046983 [protein dimerization activity] Show all	337 aa 38.7 kDa	No	0
NEUROD6-201 ENSP00000479428 ENST00000611245	A0A087WVG7 [Direct mapping] Neurogenic differentiation factor Show all	Predicted intracellular proteins Show all	GO:0003677 [DNA binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0007399 [nervous system development] GO:0030154 [cell differentiation] GO:0046983 [protein dimerization activity] Show all	330 aa 37.5 kDa	No	0