Expression of C7orf60 in cancer - Summary - The Human Protein Atlas

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C7orf60

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	C7orf60
Gene description	Chromosome 7 open reading frame 60
Protein class	Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Mixed

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression in several tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA044405
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA044405

GENE INFORMATION
Gene name	C7orf60 (HGNC Symbol)
Synonyms	DKFZp762M126, FLJ31818
Description	Chromosome 7 open reading frame 60 (HGNC Symbol)
Entrez gene summary
Chromosome	7
Cytoband	q31.1
Chromosome location (bp)	112819147 - 112939916
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000164603 (version 83.38)
Entrez gene	154743
UniProt	Q1RMZ1 (UniProt - Evidence at transcript level)
neXtProt	NX_Q1RMZ1
Antibodypedia	C7orf60 antibodies

PROTEIN BROWSER

C7orf60-001	C7orf60-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
C7orf60-001 ENSP00000297145 ENST00000297145	Q1RMZ1 [Direct mapping] Probable methyltransferase BTM2 homolog Show all	SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0016433 [rRNA (adenine) methyltransferase activity] GO:0031167 [rRNA methylation] Show all	405 aa 46.3 kDa	No	0
C7orf60-002 ENSP00000408654 ENST00000432572	H0Y6Y0 [Direct mapping] Probable methyltransferase BTM2 homolog Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0016433 [rRNA (adenine) methyltransferase activity] GO:0031167 [rRNA methylation] Show all	387 aa 44.7 kDa	No	1

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.