Cell atlas - AQP7 - The Human Protein Atlas

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AQP7

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	AQP7
Gene description	Aquaporin 7
Protein class	Predicted intracellular proteins Predicted membrane proteins Transporters
Predicted localization	Intracellular,Membrane
Number of transcripts	9
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Cell line enhanced (ASC TERT1, TIME, Hep G2, CACO-2, A549)
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (ASC TERT1, TIME, Hep G2, CACO-2, A549) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	AQP7 (HGNC Symbol)
Synonyms	AQP7L, AQP9, AQPap
Description	Aquaporin 7 (HGNC Symbol)
Entrez gene summary	Aquaporins/major intrinsic protein (MIP) are a family of water-selective membrane channels. Aquaporin 7 has greater sequence similarity with AQP3 and AQP9 and they may be a subfamily. Aquaporin 7 and AQP3 are at the same chromosomal location suggesting that 9p13 may be a site of an aquaporin cluster. Aquaporin 7 facilitates water, glycerol and urea transport. It may play an important role in sperm function. [provided by RefSeq, Jul 2008]
Chromosome	9
Cytoband	p13.3
Chromosome location (bp)	33383179 - 33402682
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000165269 (version 83.38)
Entrez gene	364
UniProt	O14520 (UniProt - Evidence at protein level)
neXtProt	NX_O14520
Antibodypedia	AQP7 antibodies

PROTEIN BROWSER

AQP7-001	AQP7-003	AQP7-004	AQP7-006	AQP7-007	AQP7-009	AQP7-014	AQP7-015	AQP7-017

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
AQP7-001 ENSP00000368821 ENST00000379507	Q5T5M1 [Direct mapping] Aquaporin-7 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 6TM proteins predicted by MDM Show all	GO:0005215 [transporter activity] GO:0005623 [cell] GO:0006810 [transport] GO:0009992 [cellular water homeostasis] GO:0015204 [urea transmembrane transporter activity] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0034220 [ion transmembrane transport] GO:0071918 [urea transmembrane transport] Show all	341 aa 37 kDa	No	6
AQP7-003 ENSP00000368820 ENST00000379506	Q5T5M0 [Direct mapping] Aquaporin-7; cDNA FLJ52444, highly similar to Aquaporin-7 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 5TM proteins predicted by MDM Show all	GO:0005215 [transporter activity] GO:0005623 [cell] GO:0006810 [transport] GO:0009992 [cellular water homeostasis] GO:0015204 [urea transmembrane transporter activity] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0034220 [ion transmembrane transport] GO:0071918 [urea transmembrane transport] Show all	256 aa 27.9 kDa	No	5
AQP7-004 ENSP00000396111 ENST00000377425	Q6P5T0 [Direct mapping] AQP7 protein; Aquaporin 7, isoform CRA_b; Aquaporin-7 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Show all	GO:0005215 [transporter activity] GO:0005623 [cell] GO:0006810 [transport] GO:0009992 [cellular water homeostasis] GO:0015204 [urea transmembrane transporter activity] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0034220 [ion transmembrane transport] GO:0071918 [urea transmembrane transport] Show all	216 aa 23.3 kDa	No	4
AQP7-006 ENSP00000297988 ENST00000297988	O14520 [Direct mapping] Aquaporin-7 Show all	Transporters Transporter channels and pores Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 6TM proteins predicted by MDM Show all	GO:0005215 [transporter activity] GO:0005737 [cytoplasm] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0005911 [cell-cell junction] GO:0006091 [generation of precursor metabolites and energy] GO:0006810 [transport] GO:0006833 [water transport] GO:0007588 [excretion] GO:0009992 [cellular water homeostasis] GO:0015204 [urea transmembrane transporter activity] GO:0015250 [water channel activity] GO:0015254 [glycerol channel activity] GO:0015793 [glycerol transport] GO:0016020 [membrane] GO:0034220 [ion transmembrane transport] GO:0055085 [transmembrane transport] GO:0071918 [urea transmembrane transport] Show all	342 aa 37.2 kDa	No	6
AQP7-007 ENSP00000410138 ENST00000439678	Q5T5L3 [Direct mapping] Aquaporin-7 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 3TM proteins predicted by MDM Show all	GO:0005215 [transporter activity] GO:0005623 [cell] GO:0006810 [transport] GO:0009992 [cellular water homeostasis] GO:0015204 [urea transmembrane transporter activity] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0034220 [ion transmembrane transport] GO:0071918 [urea transmembrane transport] Show all	170 aa 18.6 kDa	No	3
AQP7-009 ENSP00000485332 ENST00000624075	B7Z4U2 [Direct mapping] Aquaporin-7; cDNA FLJ60727, highly similar to Aquaporin-7 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 5TM proteins predicted by MDM Show all	GO:0005215 [transporter activity] GO:0005623 [cell] GO:0006810 [transport] GO:0009992 [cellular water homeostasis] GO:0015204 [urea transmembrane transporter activity] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0034220 [ion transmembrane transport] GO:0071918 [urea transmembrane transport] Show all	257 aa 28.1 kDa	No	5
AQP7-014 ENSP00000412868 ENST00000447660	O14520 [Direct mapping] Aquaporin-7 Show all	Transporters Transporter channels and pores Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 3TM proteins predicted by MDM Show all	GO:0005215 [transporter activity] GO:0005737 [cytoplasm] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0005911 [cell-cell junction] GO:0006091 [generation of precursor metabolites and energy] GO:0006810 [transport] GO:0006833 [water transport] GO:0007588 [excretion] GO:0009992 [cellular water homeostasis] GO:0015204 [urea transmembrane transporter activity] GO:0015250 [water channel activity] GO:0015254 [glycerol channel activity] GO:0015793 [glycerol transport] GO:0016020 [membrane] GO:0034220 [ion transmembrane transport] GO:0055085 [transmembrane transport] GO:0071918 [urea transmembrane transport] Show all	165 aa 18 kDa	No	3
AQP7-015 ENSP00000485081 ENST00000625109	A0A096LNK2 [Direct mapping] Aquaporin-7 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0005623 [cell] GO:0009992 [cellular water homeostasis] GO:0015204 [urea transmembrane transporter activity] GO:0016021 [integral component of membrane] GO:0034220 [ion transmembrane transport] GO:0071918 [urea transmembrane transport] Show all	80 aa 9 kDa	No	1
AQP7-017 ENSP00000485246 ENST00000625032	A0A096LNV7 [Direct mapping] Aquaporin-7 Show all	Predicted intracellular proteins Show all	GO:0005623 [cell] GO:0009992 [cellular water homeostasis] GO:0015204 [urea transmembrane transporter activity] GO:0034220 [ion transmembrane transport] GO:0071918 [urea transmembrane transport] Show all	50 aa 5.9 kDa	No	0

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.