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SLC7A3

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GENERAL INFORMATION

Gene name

 SLC7A3

Gene description

 Solute carrier family 7 (cationic amino acid transporter, y+ system), member 3

Protein class

 Predicted membrane proteins
Transporters

Predicted localization

 Membrane

Number of transcripts

 2
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

Summary

RNA cell category

 Cell line enriched (NTERA-2)

Protein evidence

 Evidence at protein level

Main location

 Not available

DATA RELIABILITY

Reliability score

 Pending cell analysis.

ASSAYS
RNA expression

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enriched (NTERA-2)
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

GENE INFORMATION

Gene name

 SLC7A3 (HGNC Symbol)

Synonyms

 ATRC3, CAT-3, FLJ14541

Description

 Solute carrier family 7 (cationic amino acid transporter, y+ system), member 3 (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of the solute carrier family 7. The encoded protein is a sodium-independent cationic amino acid transporter. Alternate splicing results in multiple transcripts that encoded the same protein.[provided by RefSeq, May 2010]

Chromosome

 X

Cytoband

 q13.1

Chromosome location (bp)

 70925582 - 70931125

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000165349 (version 83.38)

Entrez gene

 84889

UniProt

 Q8WY07 (UniProt - Evidence at protein level)

neXtProt

 NX_Q8WY07

Antibodypedia

 SLC7A3 antibodies

PROTEIN BROWSER
SLC7A3-001
SLC7A3-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
SLC7A3-001
ENSP00000363417
ENST00000374299
Q8WY07 [Direct mapping]
Cationic amino acid transporter 3
Show all
Transporters
   Electrochemical Potential-driven transporters
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   >9TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000064 [L-ornithine transmembrane transporter activity]
GO:0003333 [amino acid transmembrane transport]
GO:0005886 [plasma membrane]
GO:0005887 [integral component of plasma membrane]
GO:0006811 [ion transport]
GO:0006865 [amino acid transport]
GO:0015171 [amino acid transmembrane transporter activity]
GO:0015174 [basic amino acid transmembrane transporter activity]
GO:0015181 [arginine transmembrane transporter activity]
GO:0015189 [L-lysine transmembrane transporter activity]
GO:0015297 [antiporter activity]
GO:0015809 [arginine transport]
GO:0015819 [lysine transport]
GO:0015822 [ornithine transport]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0032006 [regulation of TOR signaling]
GO:0055085 [transmembrane transport]
GO:0097638 [L-arginine import across plasma membrane]
GO:1903352 [L-ornithine transmembrane transport]
GO:1903401 [L-lysine transmembrane transport]
GO:1990822 [basic amino acid transmembrane transport]
Show all
 619 aa
67.2 kDa 		No >9
SLC7A3-002
ENSP00000298085
ENST00000298085
Q8WY07 [Direct mapping]
Cationic amino acid transporter 3
Show all
Transporters
   Electrochemical Potential-driven transporters
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   >9TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000064 [L-ornithine transmembrane transporter activity]
GO:0003333 [amino acid transmembrane transport]
GO:0005886 [plasma membrane]
GO:0005887 [integral component of plasma membrane]
GO:0006811 [ion transport]
GO:0006865 [amino acid transport]
GO:0015171 [amino acid transmembrane transporter activity]
GO:0015181 [arginine transmembrane transporter activity]
GO:0015189 [L-lysine transmembrane transporter activity]
GO:0015297 [antiporter activity]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0055085 [transmembrane transport]
GO:0097638 [L-arginine import across plasma membrane]
GO:1903352 [L-ornithine transmembrane transport]
GO:1903401 [L-lysine transmembrane transport]
Show all
 619 aa
67.2 kDa 		No >9

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.