Cell atlas - SNAPC4 - The Human Protein Atlas

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SNAPC4

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Nuclear membrane
	Nucleoplasm

Human cell
	Nuclear membrane
	Nucleoplasm

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GENERAL INFORMATION
Gene name	SNAPC4
Gene description	Small nuclear RNA activating complex, polypeptide 4, 190kDa
Protein class	Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the nuclear membrane & nucleoplasm.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoplasm (approved), Nuclear membrane (approved)
Single-cell variation	Single-cell variation in protein expression observed.

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA073243
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the nuclear membrane & nucleoplasm.

Main location

Nucleoplasm (approved), Nuclear membrane (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA073243	HEK 293	Nucleoplasm
	HPA073243	HEK 293	Nuclear membrane
	HPA073243	MCF7	Nucleoplasm	Spatial
	HPA073243	MCF7	Nuclear membrane	Spatial
	HPA073243	U-2 OS	Nucleoplasm
			Nuclear membrane
			Cytosol

GENE INFORMATION
Gene name	SNAPC4 (HGNC Symbol)
Synonyms	FLJ13451, PTFalpha, SNAP190
Description	Small nuclear RNA activating complex, polypeptide 4, 190kDa (HGNC Symbol)
Entrez gene summary
Chromosome	9
Cytoband	q34.3
Chromosome location (bp)	136375577 - 136398797
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000165684 (version 83.38)
Entrez gene	6621
UniProt	Q5SXM2 (UniProt - Evidence at protein level)
neXtProt	NX_Q5SXM2
Antibodypedia	SNAPC4 antibodies

PROTEIN BROWSER

SNAPC4-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SNAPC4-001 ENSP00000298532 ENST00000298532	Q5SXM2 [Direct mapping] snRNA-activating protein complex subunit 4 A0A024R8F4 [Target identity:100%; Query identity:100%] Small nuclear RNA activating complex, polypeptide 4, 190kDa, isoform CRA_a Show all	MEMSAT3 predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Transcription factors Helix-turn-helix domains Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003677 [DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0006355 [regulation of transcription, DNA-templated] GO:0006366 [transcription from RNA polymerase II promoter] GO:0006383 [transcription from RNA polymerase III promoter] GO:0009301 [snRNA transcription] GO:0010467 [gene expression] GO:0019185 [snRNA-activating protein complex] GO:0042795 [snRNA transcription from RNA polymerase II promoter] GO:0042796 [snRNA transcription from RNA polymerase III promoter] Show all	1469 aa 159.4 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.