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SNAPC4

GENERAL INFORMATION

Gene name

 SNAPC4

Gene description

 Small nuclear RNA activating complex, polypeptide 4, 190kDa

Protein class

 Predicted intracellular proteins
Transcription factors

Predicted localization

 Intracellular

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Expressed in all
HPA (normal tissue):Expressed in all

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY

Data reliability
description

 RNA-based expert annotation gave inconclusive results. Pending external verification.

Reliability score

 Uncertain based on 1 antibody.
HPA046627
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PROGNOSTIC SUMMARY
Prognostic marker in pancreatic cancer (favourable).
Pancreatic cancer p<0.001
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA046627

GENE INFORMATION

Gene name

 SNAPC4 (HGNC Symbol)

Synonyms

 FLJ13451, PTFalpha, SNAP190

Description

 Small nuclear RNA activating complex, polypeptide 4, 190kDa (HGNC Symbol)

Entrez gene summary

Chromosome

 9

Cytoband

 q34.3

Chromosome location (bp)

 136375577 - 136398797

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000165684 (version 83.38)

Entrez gene

 6621

UniProt

 Q5SXM2 (UniProt - Evidence at protein level)

neXtProt

 NX_Q5SXM2

Antibodypedia

 SNAPC4 antibodies

PROTEIN BROWSER
SNAPC4-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
SNAPC4-001
ENSP00000298532
ENST00000298532
Q5SXM2 [Direct mapping]
snRNA-activating protein complex subunit 4
A0A024R8F4 [Target identity:100%; Query identity:100%]
Small nuclear RNA activating complex, polypeptide 4, 190kDa, isoform CRA_a
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   MEMSAT3 predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
Transcription factors
   Helix-turn-helix domains
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0006383 [transcription from RNA polymerase III promoter]
GO:0009301 [snRNA transcription]
GO:0010467 [gene expression]
GO:0019185 [snRNA-activating protein complex]
GO:0042795 [snRNA transcription from RNA polymerase II promoter]
GO:0042796 [snRNA transcription from RNA polymerase III promoter]
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 1469 aa
159.4 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.