Cell atlas - BMS1 - The Human Protein Atlas

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BMS1

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Nucleoli
	Nucleus

Human cell
	Nucleoli
	Nucleoplasm

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GENERAL INFORMATION
Gene name	BMS1
Gene description	BMS1 ribosome biogenesis factor
Protein class	Disease related genes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the nucleoli. In addition localized to the nucleus.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoli (validated)
Additional location	In addition localized to the Nucleus (validated)

DATA RELIABILITY
Reliability score	Validated based on 2 antibodies. HPA036589 , HPA043081
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ASSAYS

RNA expression

Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the nucleoli. In addition localized to the nucleus.

Main location

Nucleoli (validated)

Additional location

Nucleus (validated)


	Toggle channels	Low High G1 S G2 M N/A

Antibody	Cell line	Location
HPA036589	A-431	Nucleus
HPA036589	A-431	Nucleoli
HPA036589	U-2 OS	Nucleus
HPA036589	U-2 OS	Nucleoli
HPA036589	U-251 MG	Nucleus
HPA036589	U-251 MG	Nucleoli
HPA043081	A-431	Nucleus
HPA043081	A-431	Nucleoli
HPA043081	U-2 OS	Nucleus
HPA043081	U-2 OS	Nucleoli
HPA043081	U-251 MG	Nucleus
HPA043081	U-251 MG	Nucleoli

GENE INFORMATION
Gene name	BMS1 (HGNC Symbol)
Synonyms	BMS1L, KIAA0187
Description	BMS1 ribosome biogenesis factor (HGNC Symbol)
Entrez gene summary	This gene likely encodes a ribosome assembly protein. A similar protein in yeast functions in 35S-rRNA processing, which includes a series of cleavage steps critical for formation of 40S ribosomes. Related pseudogenes exist on chromosomes 2, 9, 10, 15, 16, and 22.[provided by RefSeq, Mar 2009]
Chromosome	10
Cytoband	q11.21
Chromosome location (bp)	42782801 - 42834937
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000165733 (version 83.38)
Entrez gene	9790
UniProt	Q14692 (UniProt - Evidence at protein level)
neXtProt	NX_Q14692
Antibodypedia	BMS1 antibodies

PROTEIN BROWSER

BMS1-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
BMS1-001 ENSP00000363642 ENST00000374518	Q14692 [Direct mapping] Ribosome biogenesis protein BMS1 homolog Show all	THUMBUP predicted membrane proteins Predicted intracellular proteins Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005524 [ATP binding] GO:0005634 [nucleus] GO:0005730 [nucleolus] GO:0042254 [ribosome biogenesis] GO:0042255 [ribosome assembly] GO:0044822 [poly(A) RNA binding] Show all	1282 aa 145.8 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.