Expression of BMS1 in cancer - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	BMS1
Gene description	BMS1 ribosome biogenesis factor
Protein class	Disease related genes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Mainly nuclear and nucleolar expression in several different tissue types, including cytoplasmic abundance in a subset of tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA043081
	SHOW MORE

PROGNOSTIC SUMMARY
Prognostic marker in liver cancer (unfavourable).
Liver cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

STAINING SUMMARY

HPA043081

GENE INFORMATION
Gene name	BMS1 (HGNC Symbol)
Synonyms	BMS1L, KIAA0187
Description	BMS1 ribosome biogenesis factor (HGNC Symbol)
Entrez gene summary	This gene likely encodes a ribosome assembly protein. A similar protein in yeast functions in 35S-rRNA processing, which includes a series of cleavage steps critical for formation of 40S ribosomes. Related pseudogenes exist on chromosomes 2, 9, 10, 15, 16, and 22.[provided by RefSeq, Mar 2009]
Chromosome	10
Cytoband	q11.21
Chromosome location (bp)	42782801 - 42834937
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000165733 (version 83.38)
Entrez gene	9790
UniProt	Q14692 (UniProt - Evidence at protein level)
neXtProt	NX_Q14692
Antibodypedia	BMS1 antibodies

PROTEIN BROWSER

BMS1-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
BMS1-001 ENSP00000363642 ENST00000374518	Q14692 [Direct mapping] Ribosome biogenesis protein BMS1 homolog Show all	THUMBUP predicted membrane proteins Predicted intracellular proteins Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005524 [ATP binding] GO:0005634 [nucleus] GO:0005730 [nucleolus] GO:0042254 [ribosome biogenesis] GO:0042255 [ribosome assembly] GO:0044822 [poly(A) RNA binding] Show all	1282 aa 145.8 kDa	No	0