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Cancer tissues exhibited moderate to strong nuclear positivity.
GENE INFORMATION
Gene name
BRD7 (HGNC Symbol)
Synonyms
BP75, CELTIX1
Description
Bromodomain containing 7 (HGNC Symbol)
Entrez gene summary
This gene encodes a protein which is a member of the bromodomain-containing protein family. The product of this gene has been identified as a component of one form of the SWI/SNF chromatin remodeling complex, and as a protein which interacts with p53 and is required for p53-dependent oncogene-induced senescence which prevents tumor growth. Pseudogenes have been described on chromosomes 2, 3, 6, 13 and 14. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2010]