Fields »
ABOUT
HELP
BLOG
SPIC

GENERAL INFORMATION

Gene name

 SPIC

Gene description

 Spi-C transcription factor (Spi-1/PU.1 related)

Protein class

 Predicted intracellular proteins
Transcription factors

Predicted localization

 Intracellular

Number of transcripts

 1
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Tissue enhanced (testis cancer)
HPA (cell line):Not detected
HPA (normal tissue):Tissue enriched (spleen)

Protein evidence

 Evidence at transcript level

ANTIBODY IHC RELIABILITY

Reliability score

 Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Gene product is not prognostic.
Show all

RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Tissue enhanced (testis cancer)

PROTEIN EXPRESSION

Pending cancer tissue analysis

STAINING SUMMARY

 

GENE INFORMATION

Gene name

 SPIC (HGNC Symbol)

Synonyms

 MGC40611, SPI-C

Description

 Spi-C transcription factor (Spi-1/PU.1 related) (HGNC Symbol)

Entrez gene summary

Chromosome

 12

Cytoband

 q23.2

Chromosome location (bp)

 101475421 - 101486997

Protein evidence

 Evidence at transcript level (all genes)

Ensembl

 ENSG00000166211 (version 83.38)

Entrez gene

 121599

UniProt

 Q8N5J4 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q8N5J4

Antibodypedia

 SPIC antibodies

PROTEIN BROWSER
SPIC-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
SPIC-001
ENSP00000448580
ENST00000551346
Q8N5J4 [Direct mapping]
Transcription factor Spi-C
Show all
Predicted intracellular proteins
Transcription factors
   Helix-turn-helix domains
Show all
GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding]
GO:0001824 [blastocyst development]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006357 [regulation of transcription from RNA polymerase II promoter]
GO:0030154 [cell differentiation]
GO:0043565 [sequence-specific DNA binding]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
Show all
 248 aa
29.2 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.