Tissue expression of SPIC - Summary - The Human Protein Atlas

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SPIC

TISSUE

CELL

PATHOLOGY

TISSUE ATLAS

GENE/PROTEIN

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	SPIC
Gene description	Spi-C transcription factor (Spi-1/PU.1 related)
Protein class	Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enriched (spleen)
GTEx:	Tissue enriched (spleen)
FANTOM5:	Tissue enriched (spleen)

Protein evidence

Evidence at transcript level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

N/A

Caudate

N/A

N/A

Cerebellum

N/A

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

N/A

Bronchus

N/A

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (spleen)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (spleen)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (spleen)

GENE INFORMATION
Gene name	SPIC (HGNC Symbol)
Synonyms	MGC40611, SPI-C
Description	Spi-C transcription factor (Spi-1/PU.1 related) (HGNC Symbol)
Entrez gene summary
Chromosome	12
Cytoband	q23.2
Chromosome location (bp)	101475421 - 101486997
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000166211 (version 83.38)
Entrez gene	121599
UniProt	Q8N5J4 (UniProt - Evidence at transcript level)
neXtProt	NX_Q8N5J4
Antibodypedia	SPIC antibodies

PROTEIN BROWSER

SPIC-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SPIC-001 ENSP00000448580 ENST00000551346	Q8N5J4 [Direct mapping] Transcription factor Spi-C Show all	Predicted intracellular proteins Transcription factors Helix-turn-helix domains Show all	GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding] GO:0001824 [blastocyst development] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0030154 [cell differentiation] GO:0043565 [sequence-specific DNA binding] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] Show all	248 aa 29.2 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.