Expression of CDYL2 in cancer - Summary - The Human Protein Atlas

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CDYL2

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	CDYL2
Gene description	Chromodomain protein, Y-like 2
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Cell line enhanced (HUVEC TERT2, MCF7, TIME)
HPA (normal tissue):	Mixed

Protein evidence

Evidence at protein level

Protein expression
normal tissue

General nuclear expression.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data.
Reliability score	Approved based on 1 antibody. HPA041016
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PROGNOSTIC SUMMARY
Prognostic marker in endometrial cancer (favourable).
Endometrial cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA041016

GENE INFORMATION
Gene name	CDYL2 (HGNC Symbol)
Synonyms	FLJ38866
Description	Chromodomain protein, Y-like 2 (HGNC Symbol)
Entrez gene summary
Chromosome	16
Cytoband	q23.2
Chromosome location (bp)	80597906 - 80804329
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000166446 (version 83.38)
Entrez gene	124359
UniProt	Q8N8U2 (UniProt - Evidence at protein level)
neXtProt	NX_Q8N8U2
Antibodypedia	CDYL2 antibodies

PROTEIN BROWSER

CDYL2-001	CDYL2-002	CDYL2-003	CDYL2-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CDYL2-001 ENSP00000476295 ENST00000570137	Q8N8U2 [Direct mapping] Chromodomain Y-like protein 2 Show all	Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003824 [catalytic activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0008152 [metabolic process] GO:0035064 [methylated histone binding] Show all	506 aa 56.5 kDa	No	0
CDYL2-002 ENSP00000455111 ENST00000563890	A0A0B4J291 [Direct mapping] Chromodomain Y-like protein 2 Show all	Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003824 [catalytic activity] GO:0005634 [nucleus] GO:0008152 [metabolic process] Show all	507 aa 56.6 kDa	No	0
CDYL2-003 ENSP00000456934 ENST00000566173	A0A0B4J291 [Direct mapping] Chromodomain Y-like protein 2 Show all	Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003824 [catalytic activity] GO:0005634 [nucleus] GO:0008152 [metabolic process] Show all	507 aa 56.6 kDa	No	0
CDYL2-004 ENSP00000454546 ENST00000562812	A0A0B4J291 [Direct mapping] Chromodomain Y-like protein 2 Show all	Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003824 [catalytic activity] GO:0005634 [nucleus] GO:0008152 [metabolic process] Show all	507 aa 56.6 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.