Cell atlas - SLC38A8 - The Human Protein Atlas

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SLC38A8

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	SLC38A8
Gene description	Solute carrier family 38, member 8
Protein class	Disease related genes Potential drug targets Predicted intracellular proteins Predicted membrane proteins Transporters
Predicted localization	Intracellular,Membrane
Number of transcripts	3
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Cell line enriched (SCLC-21H)
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enriched (SCLC-21H) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	SLC38A8
Synonyms
Description	Solute carrier family 38, member 8 (HGNC Symbol)
Entrez gene summary	This gene encodes a putative sodium-dependent amino-acid/proton antiporter. The protein has eleven transmembrane domains, an extracellular N-terminus and an intracellular C-terminal tail. The protein is a member of the SLC38 sodium-coupled neutral amino acid transporter family of proteins. Mutations in this gene result in foveal hypoplasia with or without optic nerve misrouting and/or anterior segment dysgenesis. [provided by RefSeq, May 2014]
Chromosome	16
Cytoband	q23.3
Chromosome location (bp)	84009667 - 84042636
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000166558 (version 83.38)
Entrez gene	146167
UniProt	A6NNN8 (UniProt - Evidence at protein level)
neXtProt	NX_A6NNN8
Antibodypedia	SLC38A8 antibodies

PROTEIN BROWSER

SLC38A8-001	SLC38A8-002	SLC38A8-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SLC38A8-001 ENSP00000299709 ENST00000299709	A6NNN8 [Direct mapping] Putative sodium-coupled neutral amino acid transporter 8 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Disease related genes Potential drug targets Show all	GO:0003333 [amino acid transmembrane transport] GO:0006814 [sodium ion transport] GO:0015171 [amino acid transmembrane transporter activity] GO:0016021 [integral component of membrane] Show all	435 aa 46.7 kDa	No	>9
SLC38A8-002 ENSP00000457737 ENST00000568178	H3BUP5 [Direct mapping] Putative sodium-coupled neutral amino acid transporter 8 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 6TM proteins predicted by MDM Show all	GO:0003333 [amino acid transmembrane transport] GO:0015171 [amino acid transmembrane transporter activity] GO:0016021 [integral component of membrane] Show all	262 aa 27.9 kDa	No	6
SLC38A8-003 ENSP00000455085 ENST00000569816	H3BP02 [Direct mapping] Putative sodium-coupled neutral amino acid transporter 8 Show all	Predicted intracellular proteins Show all	GO:0003333 [amino acid transmembrane transport] GO:0015171 [amino acid transmembrane transporter activity] Show all	46 aa 5.1 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.