Cell atlas - FAM96A - The Human Protein Atlas

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FAM96A

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol
	Nucleoplasm

Human cell
	Cytosol
	Nucleoplasm

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GENERAL INFORMATION
Gene name	FAM96A
Gene description	Family with sequence similarity 96, member A
Protein class	Predicted secreted proteins
Predicted localization	Secreted
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the nucleoplasm. In addition localized to the cytosol.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoplasm (supported)
Additional location	In addition localized to the Cytosol (supported)
Single-cell variation	Single-cell variation in protein expression observed.

DATA RELIABILITY
Reliability score	Supported based on 2 antibodies. HPA040459 , HPA063729
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ASSAYS

RNA expression

Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the nucleoplasm. In addition localized to the cytosol.

Main location

Nucleoplasm (supported)

Additional location

Cytosol (supported)


	Toggle channels	Low High G1 S G2 M N/A

Antibody	Cell line	Location	Single-cell variation
HPA040459	A-431	Nucleoplasm	Spatial
HPA040459	A-431	Cytosol	Spatial
HPA040459	U-2 OS	Nucleoplasm	Intensity
HPA040459	U-2 OS	Cytosol
HPA040459	U-251 MG	Nucleoplasm
HPA040459	U-251 MG	Cytosol
HPA063729	A549	Nucleoplasm
HPA063729	A549	Cytosol
HPA063729	MCF7	Nucleoplasm
HPA063729	U-2 OS	Nucleus	Intensity
HPA063729	U-2 OS	Cytosol	Intensity

GENE INFORMATION
Gene name	FAM96A (HGNC Symbol)
Synonyms	FLJ22875
Description	Family with sequence similarity 96, member A (HGNC Symbol)
Entrez gene summary
Chromosome	15
Cytoband	q22.31
Chromosome location (bp)	64072559 - 64094018
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000166797 (version 83.38)
Entrez gene	84191
UniProt	Q9H5X1 (UniProt - Evidence at protein level)
neXtProt	NX_Q9H5X1
Antibodypedia	FAM96A antibodies

PROTEIN BROWSER

FAM96A-001	FAM96A-002	FAM96A-004	FAM96A-006

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FAM96A-001 ENSP00000300030 ENST00000300030	Q9H5X1 [Direct mapping] MIP18 family protein FAM96A Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0005515 [protein binding] GO:0005575 [cellular_component] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0007059 [chromosome segregation] GO:0008150 [biological_process] GO:0016226 [iron-sulfur cluster assembly] GO:0046872 [metal ion binding] Show all	160 aa 18.4 kDa	Yes	0
FAM96A-002 ENSP00000369644 ENST00000380290	Q9H5X1 [Direct mapping] MIP18 family protein FAM96A Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0005515 [protein binding] GO:0005575 [cellular_component] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0007059 [chromosome segregation] GO:0008150 [biological_process] GO:0016226 [iron-sulfur cluster assembly] GO:0046872 [metal ion binding] Show all	102 aa 11.6 kDa	Yes	0
FAM96A-004 ENSP00000454079 ENST00000557835	Q9H5X1 [Direct mapping] MIP18 family protein FAM96A Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0005515 [protein binding] GO:0005575 [cellular_component] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0007059 [chromosome segregation] GO:0008150 [biological_process] GO:0016226 [iron-sulfur cluster assembly] GO:0046872 [metal ion binding] Show all	102 aa 11.6 kDa	Yes	0
FAM96A-006 ENSP00000452953 ENST00000559950	H0YKV4 [Direct mapping] Family with sequence similarity 96, member A, isoform CRA_a; MIP18 family protein FAM96A Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0007059 [chromosome segregation] GO:0016226 [iron-sulfur cluster assembly] Show all	130 aa 14.9 kDa	Yes	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.