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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

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Searches

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Expression

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Specificity

Cell line

Specificity

Cancer

Specificity

Tissue

Detectable

Cell line

Detectable

Cancer

Detectable

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Antibodies

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TERF2IP
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    TISSUE

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    CELL

  • PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation


Dictionary


Tissue proteome

GENERAL INFORMATION

Gene name

TERF2IP

Gene description

Telomeric repeat binding factor 2, interacting protein

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

2
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

Evidence at protein level

Protein expression

General nuclear expression.

DATA RELIABILITY

Data reliability
description

Antibody staining mainly consistent with RNA expression data.

Reliability score

Supported based on 3 antibodies.
HPA006719 , CAB018660 , CAB018749
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM) Protein expression (score)
Brain
Cerebral cortex
Hippocampus
N/A
Caudate
N/A
Cerebellum
N/A
Endocrine tissues
Thyroid gland
Parathyroid gland
Adrenal gland
Bone marrow & immune system
Appendix
Bone marrow
Lymph node
Tonsil
Spleen
Muscle tissues
Heart muscle
Skeletal muscle
Smooth muscle
Lung
Nasopharynx
N/A
Bronchus
N/A
Lung
Liver & gallbladder
Liver
Gallbladder
Pancreas
Pancreas
Gastrointestinal tract
Oral mucosa
N/A
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Colon
Rectum
Kidney & urinary bladder
Kidney
Urinary bladder
Male tissues
Testis
Epididymis
Prostate
Seminal vesicle
Female tissues
Breast
Vagina
N/A
Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Adipose & soft tissue
Adipose tissue
Soft tissue
N/A
Skin
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Epididymis

PROTEIN EXPRESSION OVERVIEW

Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW

HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

TERF2IP (HGNC Symbol)

Synonyms

RAP1

Description

Telomeric repeat binding factor 2, interacting protein (HGNC Symbol)

Entrez gene summary

The gene encodes a protein that is part of a complex involved in telomere length regulation. Pseudogenes are present on chromosomes 5 and 22. [provided by RefSeq, Apr 2010]

Chromosome

16

Cytoband

q23.1

Chromosome location (bp)

75647786 - 75761872

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000166848 (version 83.38)

Entrez gene

54386

UniProt

Q9NYB0 (UniProt - Evidence at protein level)

neXtProt

NX_Q9NYB0

Antibodypedia

TERF2IP antibodies

PROTEIN BROWSER

TERF2IP-001
TERF2IP-003

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TERF2IP-001
ENSP00000300086
ENST00000300086
Q9NYB0 [Direct mapping]
Telomeric repeat-binding factor 2-interacting protein 1
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000228 [nuclear chromosome]
GO:0000723 [telomere maintenance]
GO:0000781 [chromosome, telomeric region]
GO:0000783 [nuclear telomere cap complex]
GO:0000784 [nuclear chromosome, telomeric region]
GO:0003677 [DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005635 [nuclear envelope]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0007004 [telomere maintenance via telomerase]
GO:0010569 [regulation of double-strand break repair via homologous recombination]
GO:0010833 [telomere maintenance via telomere lengthening]
GO:0030870 [Mre11 complex]
GO:0031848 [protection from non-homologous end joining at telomere]
GO:0032205 [negative regulation of telomere maintenance]
GO:0033138 [positive regulation of peptidyl-serine phosphorylation]
GO:0043123 [positive regulation of I-kappaB kinase/NF-kappaB signaling]
GO:0048239 [negative regulation of DNA recombination at telomere]
GO:0051092 [positive regulation of NF-kappaB transcription factor activity]
GO:0070187 [telosome]
GO:0070198 [protein localization to chromosome, telomeric region]
GO:1901985 [positive regulation of protein acetylation]
Show all
399 aa
44.3 kDa
No 0
TERF2IP-003
ENSP00000456092
ENST00000564671
H3BR63 [Direct mapping]
Telomeric repeat-binding factor 2-interacting protein 1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
122 aa
13.3 kDa
No 0

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