Expression of MTMR10 in cancer - Summary - The Human Protein Atlas

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MTMR10

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	MTMR10
Gene description	Myotubularin related protein 10
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Nuclear expression with variable levels in most tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 1 antibody. HPA006081
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (favourable).
Renal cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

Urothelial cancer

STAINING SUMMARY

HPA006081

GENE INFORMATION
Gene name	MTMR10 (HGNC Symbol)
Synonyms	FLJ20313
Description	Myotubularin related protein 10 (HGNC Symbol)
Entrez gene summary
Chromosome	15
Cytoband	q13.3
Chromosome location (bp)	30938941 - 30991607
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000166912 (version 83.38)
Entrez gene	54893
UniProt	Q9NXD2 (UniProt - Evidence at protein level)
neXtProt	NX_Q9NXD2
Antibodypedia	MTMR10 antibodies

PROTEIN BROWSER

MTMR10-001	MTMR10-003	MTMR10-005

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
MTMR10-001 ENSP00000402537 ENST00000435680	Q9NXD2 [Direct mapping] Myotubularin-related protein 10 X5D963 [Target identity:100%; Query identity:100%] Myotubularin related protein 10 isoform C Show all	SCAMPI predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all		777 aa 88.3 kDa	No	0
MTMR10-003 ENSP00000457390 ENST00000563714	Q9NXD2 [Direct mapping] Myotubularin-related protein 10 A0A024R211 [Target identity:100%; Query identity:100%] Myotubularin related protein 10, isoform CRA_a Show all	SCAMPI predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		451 aa 51.6 kDa	No	0
MTMR10-005 ENSP00000457873 ENST00000566981	H3BUZ0 [Direct mapping] Myotubularin-related protein 10 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		303 aa 35.3 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.