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SNRPD1

GENERAL INFORMATION

Gene name

 SNRPD1

Gene description

 Small nuclear ribonucleoprotein D1 polypeptide 16kDa

Protein class

 Plasma proteins
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 General nuclear expression.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data.

Reliability score

 Supported based on 1 antibody.
HPA040516
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Nasopharynx
N/A
N/A
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Gallbladder

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 SNRPD1 (HGNC Symbol)

Synonyms

 HsT2456, Sm-D1, SNRPD

Description

 Small nuclear ribonucleoprotein D1 polypeptide 16kDa (HGNC Symbol)

Entrez gene summary

 This gene encodes a small nuclear ribonucleoprotein that belongs to the SNRNP core protein family. The protein may act as a charged protein scaffold to promote SNRNP assembly or strengthen SNRNP-SNRNP interactions through nonspecific electrostatic contacts with RNA. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014]

Chromosome

 18

Cytoband

 q11.2

Chromosome location (bp)

 21612267 - 21633524

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000167088 (version 83.38)

Entrez gene

 6632

UniProt

 P62314 (UniProt - Evidence at protein level)

neXtProt

 NX_P62314

Antibodypedia

 SNRPD1 antibodies

PROTEIN BROWSER
SNRPD1-001
SNRPD1-002
SNRPD1-003

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
SNRPD1-001
ENSP00000300413
ENST00000300413
P62314 [Direct mapping]
Small nuclear ribonucleoprotein Sm D1
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Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0000243 [commitment complex]
GO:0000245 [spliceosomal complex assembly]
GO:0000387 [spliceosomal snRNP assembly]
GO:0000398 [mRNA splicing, via spliceosome]
GO:0002230 [positive regulation of defense response to virus by host]
GO:0003723 [RNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005682 [U5 snRNP]
GO:0005685 [U1 snRNP]
GO:0005686 [U2 snRNP]
GO:0005687 [U4 snRNP]
GO:0005689 [U12-type spliceosomal complex]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0008380 [RNA splicing]
GO:0010467 [gene expression]
GO:0030532 [small nuclear ribonucleoprotein complex]
GO:0034660 [ncRNA metabolic process]
GO:0034709 [methylosome]
GO:0034715 [pICln-Sm protein complex]
GO:0034719 [SMN-Sm protein complex]
GO:0044822 [poly(A) RNA binding]
GO:0071010 [prespliceosome]
GO:0071011 [precatalytic spliceosome]
GO:0071013 [catalytic step 2 spliceosome]
GO:0097526 [spliceosomal tri-snRNP complex]
GO:0098779 [mitophagy in response to mitochondrial depolarization]
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 119 aa
13.3 kDa 		No 0
SNRPD1-002
ENSP00000463568
ENST00000582475
J3QLI9 [Direct mapping]
Small nuclear ribonucleoprotein Sm D1
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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GO:0006396 [RNA processing]
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 75 aa
8.4 kDa 		No 0
SNRPD1-003
ENSP00000463676
ENST00000579618
J3QLR7 [Direct mapping]
Small nuclear ribonucleoprotein Sm D1
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   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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GO:0006396 [RNA processing]
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 44 aa
5.3 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.