Tissue expression of TRUB2 - Summary - The Human Protein Atlas

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TRUB2

TISSUE

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CELL

PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	TRUB2
Gene description	TruB pseudouridine (psi) synthase family member 2
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Mixed
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

Protein expression

General cytoplasmic expression.

DATA RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA021211
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Mixed
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	TRUB2 (HGNC Symbol)
Synonyms	CLONE24922
Description	TruB pseudouridine (psi) synthase family member 2 (HGNC Symbol)
Entrez gene summary	Pseudouridine is an abundant component of rRNAs and tRNAs and is enzymatically generated by isomerization of uridine by pseudouridine synthase (Zucchini et al., 2003 [PubMed 12736709]).[supplied by OMIM, Mar 2008]
Chromosome	9
Cytoband	q34.11
Chromosome location (bp)	128305161 - 128322742
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000167112 (version 83.38)
Entrez gene	26995
UniProt	O95900 (UniProt - Evidence at protein level)
neXtProt	NX_O95900
Antibodypedia	TRUB2 antibodies

PROTEIN BROWSER

TRUB2-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TRUB2-001 ENSP00000361982 ENST00000372890	O95900 [Direct mapping] Probable tRNA pseudouridine synthase 2 A0A024R886 [Target identity:100%; Query identity:100%] TruB pseudouridine (Psi) synthase homolog 2 (E. coli), isoform CRA_a Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0001522 [pseudouridine synthesis] GO:0003723 [RNA binding] GO:0005737 [cytoplasm] GO:0006396 [RNA processing] GO:0008033 [tRNA processing] GO:0009451 [RNA modification] GO:0009982 [pseudouridine synthase activity] GO:0044822 [poly(A) RNA binding] Show all	331 aa 36.7 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.