Expression of TBC1D21 in cancer - Summary - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

TBC1D21

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	TBC1D21
Gene description	TBC1 domain family, member 21
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Not detected
HPA (cell line):	Not detected
HPA (normal tissue):	Tissue enriched (testis)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA043319
	SHOW MORE

PROGNOSTIC SUMMARY
Gene product is not prognostic.
Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Not detected

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA043319

GENE INFORMATION
Gene name	TBC1D21 (HGNC Symbol)
Synonyms	MGC34741, MgcRabGAP
Description	TBC1 domain family, member 21 (HGNC Symbol)
Entrez gene summary
Chromosome	15
Cytoband	q24.1
Chromosome location (bp)	73873608 - 73889214
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000167139 (version 83.38)
Entrez gene	161514
UniProt	Q8IYX1 (UniProt - Evidence at transcript level)
neXtProt	NX_Q8IYX1
Antibodypedia	TBC1D21 antibodies

PROTEIN BROWSER

TBC1D21-001	TBC1D21-002	TBC1D21-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TBC1D21-001 ENSP00000300504 ENST00000300504	Q8IYX1 [Direct mapping] TBC1 domain family member 21 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0001669 [acrosomal vesicle] GO:0003779 [actin binding] GO:0005096 [GTPase activator activity] GO:0043547 [positive regulation of GTPase activity] GO:0070062 [extracellular exosome] Show all	336 aa 39.2 kDa	No	0
TBC1D21-002 ENSP00000439325 ENST00000535547	Q8IYX1 [Direct mapping] TBC1 domain family member 21 Show all	Predicted intracellular proteins Show all	GO:0005096 [GTPase activator activity] GO:0043547 [positive regulation of GTPase activity] GO:0070062 [extracellular exosome] Show all	300 aa 35 kDa	No	0
TBC1D21-003 ENSP00000457096 ENST00000562056	H3BTA9 [Direct mapping] TBC1 domain family member 21 Show all	Predicted intracellular proteins Show all		299 aa 35 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.