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CD300C

GENERAL INFORMATION

Gene name

 CD300C

Gene description

 CD300c molecule

Protein class

 CD markers
Predicted membrane proteins

Predicted localization

 Membrane

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enhanced (lung)
GTEx:Tissue enhanced (lung, spleen)
FANTOM5:Mixed

Protein evidence

 Evidence at transcript level

Protein expression

 Cytoplasmic expression in most tissues, including immune cells.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data. Pending external verification.

Reliability score

 Approved based on 1 antibody.
HPA014523
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Appendix
N/A
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Bone marrow

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (lung)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (lung, spleen)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed

GENE INFORMATION

Gene name

 CD300C (HGNC Symbol)

Synonyms

 CMRF-35A, CMRF35, CMRF35A, IGSF16, LIR

Description

 CD300c molecule (HGNC Symbol)

Entrez gene summary

 The CMRF35 antigen, which was identified by reactivity with a monoclonal antibody, is present on monocytes, neutrophils, and some T and B lymphocytes (Jackson et al., 1992 [PubMed 1349532]).[supplied by OMIM, Mar 2008]

Chromosome

 17

Cytoband

 q25.1

Chromosome location (bp)

 74541108 - 74546143

Protein evidence

 Evidence at transcript level (all genes)

Ensembl

 ENSG00000167850 (version 83.38)

Entrez gene

 10871

UniProt

 Q08708 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q08708

Antibodypedia

 CD300C antibodies

PROTEIN BROWSER
CD300C-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
CD300C-001
ENSP00000329507
ENST00000330793
Q08708 [Direct mapping]
CMRF35-like molecule 6
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CD markers
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
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GO:0002376 [immune system process]
GO:0004888 [transmembrane signaling receptor activity]
GO:0005515 [protein binding]
GO:0005886 [plasma membrane]
GO:0005887 [integral component of plasma membrane]
GO:0006968 [cellular defense response]
GO:0007165 [signal transduction]
GO:0050776 [regulation of immune response]
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 224 aa
24.8 kDa 		Yes 1

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.