Cell atlas - ECI1 - The Human Protein Atlas

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ECI1

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TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	ECI1
Gene description	Enoyl-CoA delta isomerase 1
Protein class	Enzymes Plasma proteins Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	4
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	ECI1 (HGNC Symbol)
Synonyms	DCI
Description	Enoyl-CoA delta isomerase 1 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the hydratase/isomerase superfamily. The protein encoded is a key mitochondrial enzyme involved in beta-oxidation of unsaturated fatty acids. It catalyzes the transformation of 3-cis and 3-trans-enoyl-CoA esters arising during the stepwise degradation of cis-, mono-, and polyunsaturated fatty acids to the 2-trans-enoyl-CoA intermediates. Alternatively spliced transcript variants have been described. [provided by RefSeq, May 2010]
Chromosome	16
Cytoband	p13.3
Chromosome location (bp)	2239395 - 2252300
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000167969 (version 83.38)
Entrez gene	1632
UniProt	P42126 (UniProt - Evidence at protein level)
neXtProt	NX_P42126
Antibodypedia	ECI1 antibodies

PROTEIN BROWSER

ECI1-001	ECI1-002	ECI1-004	ECI1-005

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ECI1-001 ENSP00000301729 ENST00000301729	P42126 [Direct mapping] Enoyl-CoA delta isomerase 1, mitochondrial Show all	Enzymes ENZYME proteins Isomerase SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003824 [catalytic activity] GO:0004165 [dodecenoyl-CoA delta-isomerase activity] GO:0005739 [mitochondrion] GO:0005743 [mitochondrial inner membrane] GO:0005759 [mitochondrial matrix] GO:0006635 [fatty acid beta-oxidation] GO:0008152 [metabolic process] GO:0016860 [intramolecular oxidoreductase activity] GO:0042802 [identical protein binding] GO:0044255 [cellular lipid metabolic process] GO:0044281 [small molecule metabolic process] GO:0070062 [extracellular exosome] Show all	302 aa 32.8 kDa	No	0
ECI1-002 ENSP00000456319 ENST00000562238	P42126 [Direct mapping] Enoyl-CoA delta isomerase 1, mitochondrial Show all	Enzymes ENZYME proteins Isomerase SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003824 [catalytic activity] GO:0004165 [dodecenoyl-CoA delta-isomerase activity] GO:0005739 [mitochondrion] GO:0005759 [mitochondrial matrix] GO:0006635 [fatty acid beta-oxidation] GO:0008152 [metabolic process] GO:0016860 [intramolecular oxidoreductase activity] GO:0044255 [cellular lipid metabolic process] GO:0044281 [small molecule metabolic process] GO:0070062 [extracellular exosome] Show all	285 aa 30.9 kDa	No	0
ECI1-004 ENSP00000457900 ENST00000570258	Q96DC0 [Direct mapping] DCI protein; Dodecenoyl-Coenzyme A delta isomerase (3,2 trans-enoyl-Coenzyme A isomerase), isoform CRA_a; Enoyl-CoA delta isomerase 1, mitochondrial Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003824 [catalytic activity] GO:0008152 [metabolic process] GO:0016853 [isomerase activity] Show all	243 aa 27 kDa	No	0
ECI1-005 ENSP00000456565 ENST00000566379	H3BS70 [Direct mapping] Enoyl-CoA delta isomerase 1, mitochondrial Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003824 [catalytic activity] GO:0008152 [metabolic process] Show all	224 aa 24.7 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.