Tissue expression of GNG4 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	GNG4
Gene description	Guanine nucleotide binding protein (G protein), gamma 4
Protein class	Predicted intracellular proteins RAS pathway related proteins
Predicted localization	Intracellular
Number of transcripts	5
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enhanced (cerebral cortex, ovary, prostate)
GTEx:	Tissue enhanced (hypothalamus, pituitary gland)
FANTOM5:	Tissue enhanced (ovary, pituitary gland)

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (cerebral cortex, ovary, prostate)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (hypothalamus, pituitary gland)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (ovary, pituitary gland)

GENE INFORMATION
Gene name	GNG4
Synonyms
Description	Guanine nucleotide binding protein (G protein), gamma 4 (HGNC Symbol)
Entrez gene summary
Chromosome	1
Cytoband	q42.3
Chromosome location (bp)	235547687 - 235650754
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000168243 (version 83.38)
Entrez gene	2786
UniProt	P50150 (UniProt - Evidence at protein level)
neXtProt	NX_P50150
Antibodypedia	GNG4 antibodies

PROTEIN BROWSER

GNG4-001	GNG4-002	GNG4-003	GNG4-201	GNG4-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GNG4-001 ENSP00000355557 ENST00000366598	P50150 [Direct mapping] Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 B1APZ0 [Target identity:100%; Query identity:100%] Guanine nucleotide-binding protein subunit gamma Show all	Predicted intracellular proteins RAS pathway related proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0004871 [signal transducer activity] GO:0005515 [protein binding] GO:0005834 [heterotrimeric G-protein complex] GO:0005886 [plasma membrane] GO:0006112 [energy reserve metabolic process] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007268 [synaptic transmission] GO:0008277 [regulation of G-protein coupled receptor protein signaling pathway] GO:0030308 [negative regulation of cell growth] GO:0044281 [small molecule metabolic process] GO:0070062 [extracellular exosome] GO:0071377 [cellular response to glucagon stimulus] Show all	75 aa 8.4 kDa	No	0
GNG4-002 ENSP00000355556 ENST00000366597	P50150 [Direct mapping] Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 B1APZ0 [Target identity:100%; Query identity:100%] Guanine nucleotide-binding protein subunit gamma Show all	Predicted intracellular proteins RAS pathway related proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004871 [signal transducer activity] GO:0005515 [protein binding] GO:0005834 [heterotrimeric G-protein complex] GO:0005886 [plasma membrane] GO:0006112 [energy reserve metabolic process] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007268 [synaptic transmission] GO:0008277 [regulation of G-protein coupled receptor protein signaling pathway] GO:0030308 [negative regulation of cell growth] GO:0044281 [small molecule metabolic process] GO:0070062 [extracellular exosome] GO:0071377 [cellular response to glucagon stimulus] Show all	75 aa 8.4 kDa	No	0
GNG4-003 ENSP00000482192 ENST00000484517	P50150 [Direct mapping] Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 B1APZ0 [Target identity:100%; Query identity:100%] Guanine nucleotide-binding protein subunit gamma Show all	Predicted intracellular proteins RAS pathway related proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004871 [signal transducer activity] GO:0005515 [protein binding] GO:0005834 [heterotrimeric G-protein complex] GO:0005886 [plasma membrane] GO:0006112 [energy reserve metabolic process] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007268 [synaptic transmission] GO:0008277 [regulation of G-protein coupled receptor protein signaling pathway] GO:0030308 [negative regulation of cell growth] GO:0044281 [small molecule metabolic process] GO:0070062 [extracellular exosome] GO:0071377 [cellular response to glucagon stimulus] Show all	75 aa 8.4 kDa	No	0
GNG4-201 ENSP00000375727 ENST00000391854	P50150 [Direct mapping] Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 B1APZ0 [Target identity:100%; Query identity:100%] Guanine nucleotide-binding protein subunit gamma Show all	Predicted intracellular proteins RAS pathway related proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0004871 [signal transducer activity] GO:0005515 [protein binding] GO:0005834 [heterotrimeric G-protein complex] GO:0005886 [plasma membrane] GO:0006112 [energy reserve metabolic process] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007268 [synaptic transmission] GO:0008277 [regulation of G-protein coupled receptor protein signaling pathway] GO:0030308 [negative regulation of cell growth] GO:0044281 [small molecule metabolic process] GO:0070062 [extracellular exosome] GO:0071377 [cellular response to glucagon stimulus] Show all	75 aa 8.4 kDa	No	0
GNG4-202 ENSP00000398629 ENST00000450593	P50150 [Direct mapping] Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 B1APZ0 [Target identity:100%; Query identity:100%] Guanine nucleotide-binding protein subunit gamma Show all	Predicted intracellular proteins RAS pathway related proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0004871 [signal transducer activity] GO:0005515 [protein binding] GO:0005834 [heterotrimeric G-protein complex] GO:0005886 [plasma membrane] GO:0006112 [energy reserve metabolic process] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007268 [synaptic transmission] GO:0008277 [regulation of G-protein coupled receptor protein signaling pathway] GO:0030308 [negative regulation of cell growth] GO:0044281 [small molecule metabolic process] GO:0070062 [extracellular exosome] GO:0071377 [cellular response to glucagon stimulus] Show all	75 aa 8.4 kDa	No	0