Cell atlas - CDKN2AIP - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

CDKN2AIP

TISSUE

premium

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS GFP

GENE/PROTEIN

Antibody validation

Dictionary
	Nucleoplasm

Human cell
	Nucleoplasm

Please wait until image is loaded before changing channels

GENERAL INFORMATION
Gene name	CDKN2AIP
Gene description	CDKN2A interacting protein
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the nucleoplasm.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoplasm (validated)
GFP	The location(s) are Validated based on analysis of GFP-tagged protein.

DATA RELIABILITY
Reliability score	Validated based on 1 antibody. HPA062142
	SHOW MORE

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the nucleoplasm.

Main location

Nucleoplasm (validated)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA062142	HeLa	Nucleoplasm
	HPA062142	U-2 OS	Nucleoplasm

GFP

Antibody	HPA062142
Validation	C-terminal tag BAC cell line: 5992 Validated: Antibody staining overlaps with GFP tagged protein


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	BAC id	Tag	Location antibody staining	Location tagged protein
	HPA062142	HeLa	5992	C-terminal	Nucleoplasm	Nucleoplasm
	HPA062142	HeLa	Normal	-	Nucleoplasm, Cytosol	-

GENE INFORMATION
Gene name	CDKN2AIP (HGNC Symbol)
Synonyms	CARF, FLJ20036
Description	CDKN2A interacting protein (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene regulates the DNA damage response through several different signaling pathways. One such pathway is the p53-HDM2-p21(WAF1) pathway, which is critical to the DNA damage response. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]
Chromosome	4
Cytoband	q35.1
Chromosome location (bp)	183444591 - 183448198
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000168564 (version 83.38)
Entrez gene	55602
UniProt	Q9NXV6 (UniProt - Evidence at protein level)
neXtProt	NX_Q9NXV6
Antibodypedia	CDKN2AIP antibodies

PROTEIN BROWSER

CDKN2AIP-001	CDKN2AIP-002	CDKN2AIP-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CDKN2AIP-001 ENSP00000427108 ENST00000504169	Q9NXV6 [Direct mapping] CDKN2A-interacting protein Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0001652 [granular component] GO:0002039 [p53 binding] GO:0003723 [RNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005730 [nucleolus] GO:0005737 [cytoplasm] GO:0006974 [cellular response to DNA damage stimulus] GO:0009967 [positive regulation of signal transduction] GO:0030307 [positive regulation of cell growth] GO:0030308 [negative regulation of cell growth] GO:0031647 [regulation of protein stability] Show all	580 aa 61.1 kDa	No	0
CDKN2AIP-002 ENSP00000303788 ENST00000302350	J3KNE1 [Direct mapping] CDKN2A-interacting protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		126 aa 14 kDa	No	0
CDKN2AIP-004 ENSP00000421308 ENST00000510928	D6RGD2 [Direct mapping] CDKN2A-interacting protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		135 aa 14.9 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.