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JMJD7-PLA2G4B

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GENERAL INFORMATION

Gene name

 JMJD7-PLA2G4B

Gene description

 JMJD7-PLA2G4B readthrough

Protein class

 Enzymes
Predicted intracellular proteins
RAS pathway related proteins

Predicted localization

 Intracellular

Number of transcripts

 3
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HUMAN PROTEIN ATLAS INFORMATION

Summary

 Localized to the cytosol. Caution: Based on antibodies targeting proteins from multiple genes.

RNA cell category

 Cell line enhanced (RT4)

Protein evidence

 Evidence at protein level

Main location

 Localized to the Cytosol (approved)

DATA RELIABILITY

Reliability score

 Approved based on 1 antibody.
HPA005726
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ASSAYS
RNA expression
Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (RT4)
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

HUMAN CELLS

Summary

 Localized to the cytosol. Caution: Based on antibodies targeting proteins from multiple genes.

Main location

 Cytosol (approved)

 

 

 
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Low
High
G1
S
G2
M
N/A

Thumbnail

Antibody

Cell line

Location

Single-cell variation

Cell cycle dependent variation
HPA005726 U-2 OS Cytosol
HPA005726 U-251 MG Cytosol

GENE INFORMATION

Gene name

 JMJD7-PLA2G4B

Synonyms

Description

 JMJD7-PLA2G4B readthrough (HGNC Symbol)

Entrez gene summary

 This locus represents naturally-occurring readthrough transcription between the neighboring jumonji domain containing 7 (JMJD7) and phospholipase A2, group IVB (cytosolic) (PLA2G4B) genes. Readthrough transcripts encode fusion proteins that share amino acid sequence with each individual gene product, including a partial JmjC domain and downstream C2 and phospholipase A2 domains. Alternatively spliced transcript variants have been observed. [provided by RefSeq, Oct 2013]

Chromosome

 15

Cytoband

 q15.1

Chromosome location (bp)

 41828095 - 41848155

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000168970 (version 83.38)

Entrez gene

 8681

UniProt

 P0C869 (UniProt - Evidence at protein level)

neXtProt

 NX_P0C869

Antibodypedia

 JMJD7-PLA2G4B antibodies

PROTEIN BROWSER
JMJD7-PLA2G4B-001
JMJD7-PLA2G4B-002
JMJD7-PLA2G4B-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
JMJD7-PLA2G4B-001
ENSP00000371886
ENST00000382448
   MEMSAT3 predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
RAS pathway related proteins
Show all
GO:0004620 [phospholipase activity]
GO:0005515 [protein binding]
GO:0008152 [metabolic process]
GO:0009395 [phospholipid catabolic process]
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 1012 aa
114.1 kDa 		No 0
JMJD7-PLA2G4B-002
ENSP00000342785
ENST00000342159
   MEMSAT3 predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
RAS pathway related proteins
Show all
GO:0004620 [phospholipase activity]
GO:0005515 [protein binding]
GO:0008152 [metabolic process]
GO:0009395 [phospholipid catabolic process]
Show all
 893 aa
100.5 kDa 		No 0
JMJD7-PLA2G4B-201
ENSP00000416610
ENST00000458483
P0C869 [Direct mapping]
Cytosolic phospholipase A2 beta
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Enzymes
   ENZYME proteins
   Hydrolases
   MEMSAT3 predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
RAS pathway related proteins
Show all
GO:0004620 [phospholipase activity]
GO:0004622 [lysophospholipase activity]
GO:0005509 [calcium ion binding]
GO:0005515 [protein binding]
GO:0005544 [calcium-dependent phospholipid binding]
GO:0005576 [extracellular region]
GO:0005743 [mitochondrial inner membrane]
GO:0005829 [cytosol]
GO:0006644 [phospholipid metabolic process]
GO:0006654 [phosphatidic acid biosynthetic process]
GO:0006954 [inflammatory response]
GO:0007567 [parturition]
GO:0008152 [metabolic process]
GO:0009395 [phospholipid catabolic process]
GO:0019369 [arachidonic acid metabolic process]
GO:0019722 [calcium-mediated signaling]
GO:0030968 [endoplasmic reticulum unfolded protein response]
GO:0031901 [early endosome membrane]
GO:0036148 [phosphatidylglycerol acyl-chain remodeling]
GO:0036150 [phosphatidylserine acyl-chain remodeling]
GO:0036151 [phosphatidylcholine acyl-chain remodeling]
GO:0036152 [phosphatidylethanolamine acyl-chain remodeling]
GO:0036498 [IRE1-mediated unfolded protein response]
GO:0044267 [cellular protein metabolic process]
GO:0044281 [small molecule metabolic process]
GO:0046474 [glycerophospholipid biosynthetic process]
GO:0046475 [glycerophospholipid catabolic process]
GO:0047498 [calcium-dependent phospholipase A2 activity]
Show all
 781 aa
88 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.