Cell atlas - ASMTL - The Human Protein Atlas

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ASMTL

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol

Human cell
	Cytosol

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GENERAL INFORMATION
Gene name	ASMTL
Gene description	Acetylserotonin O-methyltransferase-like
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the cytosol.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Cytosol (validated)

DATA RELIABILITY
Reliability score	Validated based on 2 antibodies. HPA003630 , HPA021865
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ASSAYS

RNA expression

Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the cytosol.

Main location

Cytosol (validated)


	Toggle channels	Low High G1 S G2 M N/A

Antibody	Cell line	Location
HPA021865	A-431	Cytosol
HPA021865	U-2 OS	Cytosol
HPA021865	U-251 MG	Cytosol
HPA003630	A-431	Cytosol
HPA003630	U-2 OS	Cytosol

GENE INFORMATION
Gene name	ASMTL
Synonyms
Description	Acetylserotonin O-methyltransferase-like (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene has an N-terminus that is similar to the multicopy associated filamentation (maf) protein of Bacillus subtilis and to orfE of Escherichia coli, while the C-terminus is similar to N-acetylserotonin O-methyltransferase. This gene is located in the pseudoautosomal region 1 (PAR1) of X and Y chromosomes. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]
Chromosome	X
Cytoband	p22.33
Chromosome location (bp)	1403139 - 1453762
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000169093 (version 83.38)
Entrez gene	8623
UniProt	O95671 (UniProt - Evidence at protein level)
neXtProt	NX_O95671
Antibodypedia	ASMTL antibodies

PROTEIN BROWSER

ASMTL-001	ASMTL-005	ASMTL-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ASMTL-001 ENSP00000370734 ENST00000381333	O95671 [Direct mapping] N-acetylserotonin O-methyltransferase-like protein Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0008150 [biological_process] GO:0008168 [methyltransferase activity] GO:0008171 [O-methyltransferase activity] GO:0032259 [methylation] Show all	605 aa 67.2 kDa	No	0
ASMTL-005 ENSP00000370718 ENST00000381317	O95671 [Direct mapping] N-acetylserotonin O-methyltransferase-like protein Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0008150 [biological_process] GO:0008168 [methyltransferase activity] GO:0008171 [O-methyltransferase activity] GO:0032259 [methylation] Show all	621 aa 68.9 kDa	No	0
ASMTL-201 ENSP00000446410 ENST00000534940	O95671 [Direct mapping] N-acetylserotonin O-methyltransferase-like protein Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0008150 [biological_process] GO:0008168 [methyltransferase activity] GO:0008171 [O-methyltransferase activity] GO:0032259 [methylation] Show all	563 aa 62.4 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.